YAF9/YNL107W Summary Help

YAF9 BASIC INFORMATION

Standard Name YAF9
Systematic Name YNL107W
Feature Type ORF, Verified
Description Subunit of both the NuA4 histone H4 acetyltransferase complex and the SWR1 complex, may function to antagonize silencing near telomeres; interacts directly with Swc4p, has homology to human leukemogenic protein AF9, contains a YEATS domain (1, 2)
Name Description Yeast homolog of the human leukemogenic protein AF9 2
GO Annotations All YAF9 GO evidence and references
    View Computational GO annotations for YAF9
Molecular Function
Manually curated
Biological Process
Manually curated
High-throughput
Cellular Component
Manually curated
High-throughput
Mutant Phenotype All YAF9 Phenotype details and references
Classical genetics
null
Large-scale survey
null
Interactions YAF9 All interactions details and references
465 total interaction(s) for 262 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 80
  • Affinity Capture-RNA: 1
  • Affinity Capture-Western: 25
  • Two-hybrid: 5
Genetic Interactions
  • Dosage Rescue: 2
  • Phenotypic Enhancement: 123
  • Phenotypic Suppression: 28
  • Synthetic Growth Defect: 103
  • Synthetic Lethality: 94
  • Synthetic Rescue: 4
Sequence Information
ChrXIV:420100 to 420780 | ORF Map | GBrowse
Gbrowse
Last Update Coordinates: 2005-11-07 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..681 420100..420780 2005-11-07 1996-07-31
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000005051

YAF9 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
 GBrowse
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  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
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  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

ADDITIONAL INFORMATION for YAF9

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for YAF9]

1) Bittner CB, et al.  (2004) Direct physical and functional interaction of the NuA4 complex components Yaf9p and Swc4p. Eukaryot Cell 3(4):976-83
2) Zhang H, et al.  (2004) The Yaf9 component of the SWR1 and NuA4 complexes is required for proper gene expression, histone H4 acetylation, and Htz1 replacement near telomeres. Mol Cell Biol 24(21):9424-36