EOS1/YNL080C Summary Help

Standard Name EOS1 1
Systematic Name YNL080C
Feature Type ORF, Verified
Description Protein involved in N-glycosylation; deletion mutation confers sensitivity to exidative stress and shows synthetic lethality with mutations in the spindle checkpoint genes BUB3 and MAD1; YNL080C is not an essential gene (1, 2, 3, 4)
Name Description ER-localized and Oxidants Sensitive 1
Chromosomal Location
ChrXIV:478032 to 476932 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All EOS1 GO evidence and references
  View Computational GO annotations for EOS1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 2 genes
Resources
Classical genetics
null
Large-scale survey
null
overexpression
Resources
197 total interaction(s) for 186 unique genes/features.
Physical Interactions
  • Biochemical Activity: 1
  • Protein-RNA: 1

Genetic Interactions
  • Dosage Rescue: 1
  • Negative Genetic: 134
  • Phenotypic Enhancement: 9
  • Phenotypic Suppression: 15
  • Positive Genetic: 19
  • Synthetic Growth Defect: 10
  • Synthetic Lethality: 3
  • Synthetic Rescue: 4

Resources
Expression Summary
histogram
Resources
Length (a.a.) 366
Molecular Weight (Da) 41,673
Isoelectric Point (pI) 5.87
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXIV:478032 to 476932 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1101 478032..476932 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000005024
References cited on this page View Complete Literature Guide for EOS1
1) Nakamura T, et al.  (2007) EOS1, whose deletion confers sensitivity to oxidative stress, is involved in N-glycosylation in Saccharomyces cerevisiae. Biochem Biophys Res Commun 353(2):293-8
2) Brachat A, et al.  (2000) Analysis of deletion phenotypes and GFP fusions of 21 novel Saccharomyces cerevisiae open reading frames. Yeast 16(3):241-53
3) Giaever G, et al.  (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91
4) Daniel JA, et al.  (2006) Diverse functions of spindle assembly checkpoint genes in Saccharomyces cerevisiae. Genetics 172(1):53-65