Standard Name	NIS1 1
Systematic Name	YNL078W
Alias	JIP1
Feature Type	ORF, Verified
Description	Protein localized in the bud neck at G2/M phase; physically interacts with septins; possibly involved in a mitotic signaling network (1)
Name Description	Neck protein Interacting with Septins 1

Chromosomal Location	ChrXIV:479768 to 480991 | ORF Map | GBrowse

	View Computational GO annotations for NIS1
Molecular Function
Manually curated	molecular_function unknown (ND)
Biological Process
Manually curated	regulation of mitosis (IPI)
Cellular Component
Manually curated	cellular bud neck (IDA) nucleus (IDA)

Classical genetics
null	viable
Large-scale survey
null	competitive fitness: decreased hyperosmotic stress resistance: decreased metal resistance: decreased resistance to amiodarone: decreased resistance to methyl methanesulfonate: decreased vacuolar morphology: abnormal viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	67 total interaction(s) for 45 unique genes/features.
Physical Interactions	Affinity Capture-MS: 14 Affinity Capture-RNA: 3 Affinity Capture-Western: 3 Biochemical Activity: 1 PCA: 1 Two-hybrid: 37
Genetic Interactions	Negative Genetic: 6 Positive Genetic: 1 Synthetic Growth Defect: 1
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP
Homologs	Ashbya (AGD) | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrXIV:479768 to 480991 | ORF Map | GBrowse
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..1224 479768..480991 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB382 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain M22 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000005022