COG5/YNL051W Summary Help

Standard Name COG5 1
Systematic Name YNL051W
Alias API4 2 , COD4 1
Feature Type ORF, Verified
Description Component of the conserved oligomeric Golgi complex; a cytosolic tethering complex (Cog1p through Cog8p) that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments (1, 3)
Name Description Conserved Oligomeric Golgi complex 1
Chromosomal Location
ChrXIV:532659 to 533870 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All COG5 GO evidence and references
  View Computational GO annotations for COG5
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 3 genes
Resources
Classical genetics
reduction of function
Large-scale survey
null
Resources
606 total interaction(s) for 263 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 25
  • Affinity Capture-Western: 11
  • Two-hybrid: 5

Genetic Interactions
  • Negative Genetic: 443
  • Phenotypic Enhancement: 62
  • Phenotypic Suppression: 6
  • Positive Genetic: 27
  • Synthetic Growth Defect: 16
  • Synthetic Lethality: 11

Resources
Expression Summary
histogram
Resources
Length (a.a.) 403
Molecular Weight (Da) 45,604
Isoelectric Point (pI) 9.48
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXIV:532659 to 533870 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1997-01-28
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1212 532659..533870 2011-02-03 1997-01-28
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000004996
References cited on this page View Complete Literature Guide for COG5
1) Ram RJ, et al.  (2002) Identification of Sec36p, Sec37p, and Sec38p: components of yeast complex that contains Sec34p and Sec35p. Mol Biol Cell 13(5):1484-500
2) Bidlingmaier S and Snyder M  (2002) Large-scale identification of genes important for apical growth in Saccharomyces cerevisiae by directed allele replacement technology (DART) screening. Funct Integr Genomics 1(6):345-56
3) Loh E and Hong W  (2004) The binary interacting network of the conserved oligomeric Golgi tethering complex. J Biol Chem 279(23):24640-8