Standard Name	PET8
Systematic Name	YNL003C
Alias	SAM5
Feature Type	ORF, Verified
Description	S-adenosylmethionine transporter of the mitochondrial inner membrane, member of the mitochondrial carrier family; required for biotin biosynthesis and respiratory growth (1, 2)
Name Description	PETite colonies

Chromosomal Location	ChrXIV:625829 to 624975 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
	Genetic position: 3 cM

	View Computational GO annotations for PET8
Molecular Function
Manually curated	S-adenosyl-L-methionine transmembrane transporter activity (IDA, IGI, IMP)
Biological Process
Manually curated	S-adenosyl-L-methionine transport (IDA, IGI, IMP)
Cellular Component
Manually curated	mitochondrial inner membrane (ISS) mitochondrion (IDA)
High-throughput	integral to membrane (ISM) mitochondrion (IDA)

Classical genetics
null	auxotrophy respiratory growth: absent
Large-scale survey
null	acid pH resistance: decreased cell cycle progression in G1 phase: increased duration glycogen accumulation: decreased chitin deposition: increased competitive fitness: decreased dessication resistance: decreased oxidative stress resistance: decreased resistance to acrolein: decreased resistance to Calcofluor White: normal respiratory growth: decreased rate respiratory growth: absent stress resistance: increased vacuolar morphology: abnormal viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	161 total interaction(s) for 127 unique genes/features.
Physical Interactions	Affinity Capture-RNA: 2 PCA: 5
Genetic Interactions	Negative Genetic: 111 Phenotypic Enhancement: 1 Positive Genetic: 35 Synthetic Growth Defect: 3 Synthetic Lethality: 3 Synthetic Rescue: 1
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder | YeastRC Two-Hybrid

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrXIV:625829 to 624975 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
	Genetic position: 3 cM
Last Update	Coordinates: 2011-02-03 | Sequence: 1997-01-28
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..855 625829..624975 2011-02-03 1997-01-28
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB382 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | TCDB | UniProtKB

Primary SGDID	S000004948