RLP7/YNL002C Summary Help

Standard Name RLP7 1
Systematic Name YNL002C
Alias RPL7
Feature Type ORF, Verified
Description Nucleolar protein similar to large ribosomal subunit L7 proteins; constituent of 66S pre-ribosomal particles; plays an essential role in processing of precursors to the large ribosomal subunit RNAs; binds junction of ITS2 and ITS2-proximal stem between the 3' end of 5.8S rRNA and the 5' end of 25S rRNA (1, 2, 3, 4)
Name Description Ribosomal-Like Protein 1
Chromosomal Location
ChrXIV:627142 to 626174 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All RLP7 GO evidence and references
Molecular Function
Manually curated
High-throughput
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 3 genes
Resources
Classical genetics
conditional
null
Large-scale survey
conditional
null
reduction of function
Resources
508 total interaction(s) for 372 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 432
  • Affinity Capture-RNA: 3
  • Affinity Capture-Western: 5
  • Co-purification: 5
  • PCA: 4
  • Two-hybrid: 7

Genetic Interactions
  • Dosage Rescue: 1
  • Negative Genetic: 40
  • Positive Genetic: 7
  • Synthetic Lethality: 4

Resources
Expression Summary
histogram
Resources
Length (a.a.) 322
Molecular Weight (Da) 36,559
Isoelectric Point (pI) 10.24
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXIV:627142 to 626174 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1997-01-28
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..969 627142..626174 2011-02-03 1997-01-28
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000004947
References cited on this page View Complete Literature Guide for RLP7
1) Lalo D, et al.  (1993) Two distinct yeast proteins are related to the mammalian ribosomal polypeptide L7. Yeast 9(10):1085-91
2) Dunbar DA, et al.  (2000) A nucleolar protein related to ribosomal protein L7 is required for an early step in large ribosomal subunit biogenesis. Proc Natl Acad Sci U S A 97(24):13027-32
3) Horsey EW, et al.  (2004) Role of the yeast Rrp1 protein in the dynamics of pre-ribosome maturation. RNA 10(5):813-27
4) Dembowski JA, et al.  (2013) Identification of the binding site of Rlp7 on assembling 60S ribosomal subunits in Saccharomyces cerevisiae. RNA 19(12):1639-47