SNO4/YMR322C Summary Help

Standard Name SNO4 1
Systematic Name YMR322C
Alias HSP34 2
Feature Type ORF, Verified
Description Possible chaperone and cysteine protease; required for transcriptional reprogramming during the diauxic shift and for survival in stationary phase; similar to bacterial Hsp31 and yeast Hsp31p, Hsp32p, and Hsp33p; DJ-1/ThiJ/PfpI superfamily member; predicted involvement in pyridoxine metabolism; induced by mild heat stress and copper deprivation (1, 2, 3, 4, 5)
Name Description SNZ proximal Open reading frame 1
Chromosomal Location
ChrXIII:919079 to 918366 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gene Ontology Annotations All SNO4 GO evidence and references
  View Computational GO annotations for SNO4
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 3 genes
Classical genetics
Large-scale survey
58 total interaction(s) for 57 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 1
  • PCA: 1
  • Two-hybrid: 6

Genetic Interactions
  • Negative Genetic: 43
  • Positive Genetic: 5
  • Synthetic Growth Defect: 2

Expression Summary
Length (a.a.) 237
Molecular Weight (Da) 26,039
Isoelectric Point (pI) 8.4
Phosphorylation PhosphoGRID | PhosphoPep Database
sequence information
ChrXIII:919079 to 918366 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Most Recent Updates
Coordinates Sequence
CDS 1..714 919079..918366 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000004941
References cited on this page View Complete Literature Guide for SNO4
1) Samanta MP and Liang S  (2003) Predicting protein functions from redundancies in large-scale protein interaction networks. Proc Natl Acad Sci U S A 100(22):12579-83
2) Wilson MA, et al.  (2004) The 1.8-A resolution crystal structure of YDR533Cp from Saccharomyces cerevisiae: A member of the DJ-1/ThiJ/PfpI superfamily. Proc Natl Acad Sci U S A 101(6):1531-6
3) van Bakel H, et al.  (2005) Gene expression profiling and phenotype analyses of S. cerevisiae in response to changing copper reveals six genes with new roles in copper and iron metabolism. Physiol Genomics 22(3):356-67
4) Sakaki K, et al.  (2003) Response of genes associated with mitochondrial function to mild heat stress in yeast Saccharomyces cerevisiae. J Biochem 134(3):373-84
5) Miller-Fleming L, et al.  (2014) Yeast DJ-1 superfamily members are required for diauxic-shift reprogramming and cell survival in stationary phase. Proc Natl Acad Sci U S A 111(19):7012-7