NIP1/YMR309C Summary Help

Standard Name NIP1 1
Systematic Name YMR309C
Feature Type ORF, Verified
Description eIF3c subunit of the eukaryotic translation initiation factor 3 (eIF3); involved in the assembly of preinitiation complex and start codon selection (1, 2)
Name Description Nuclear ImPort 1
Chromosomal Location
ChrXIII:895426 to 892988 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All NIP1 GO evidence and references
  View Computational GO annotations for NIP1
Molecular Function
Manually curated
High-throughput
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 10 genes
Resources
Classical genetics
conditional
repressible
Large-scale survey
null
overexpression
reduction of function
unspecified
Resources
218 total interaction(s) for 89 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 126
  • Affinity Capture-RNA: 2
  • Affinity Capture-Western: 36
  • Biochemical Activity: 1
  • Co-fractionation: 3
  • Co-purification: 5
  • PCA: 1
  • Reconstituted Complex: 18
  • Two-hybrid: 16

Genetic Interactions
  • Dosage Rescue: 1
  • Phenotypic Suppression: 1
  • Synthetic Growth Defect: 5
  • Synthetic Lethality: 1
  • Synthetic Rescue: 2

Resources
Expression Summary
histogram
Resources
Length (a.a.) 812
Molecular Weight (Da) 93,203
Isoelectric Point (pI) 4.69
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXIII:895426 to 892988 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..2439 895426..892988 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000004926
References cited on this page View Complete Literature Guide for NIP1
1) Gu Z, et al.  (1992) NIP1, a gene required for nuclear transport in yeast. Proc Natl Acad Sci U S A 89(21):10355-9
2) Valasek L, et al.  (2003) The yeast eIF3 subunits TIF32/a, NIP1/c, and eIF5 make critical connections with the 40S ribosome in vivo. Genes Dev 17(6):786-99