Standard Name	JNM1 1
Systematic Name	YMR294W
Alias	INS1 , PAC3 2
Feature Type	ORF, Verified
Description	Component of the yeast dynactin complex, consisting of Nip100p, Jnm1p, and Arp1p; required for proper nuclear migration and spindle partitioning during mitotic anaphase B (1, 3)
Name Description	Just Nuclear Migration 1

Chromosomal Location	ChrXIII:856966 to 858087 | ORF Map | GBrowse

	View Computational GO annotations for JNM1
Molecular Function
Manually curated	structural constituent of cytoskeleton (IPI)
Biological Process
Manually curated	establishment of mitotic spindle orientation (IMP) nuclear migration (IMP)
Cellular Component
Manually curated	colocalizes_with astral microtubule (IDA) colocalizes_with cell cortex (IDA) dynactin complex (IDA) colocalizes_with spindle pole body (IDA)

Classical genetics
null	nuclear position: abnormal resistance to staurosporine: decreased resistance to tunicamycin: decreased resistance to Calcofluor White: decreased
reduction of function	nuclear position: abnormal
Large-scale survey
null	competitive fitness: decreased dessication resistance: decreased resistance to benomyl: decreased resistance to cycloheximide: decreased resistance to amitrole: decreased resistance to benzo[a]pyrene: increased resistance to sodium arsenite: decreased resistance to dimethyl sulfoxide: decreased resistance to ethanol: decreased resistance to sirolimus: decreased starvation resistance: decreased stress resistance: decreased vacuolar morphology: abnormal vegetative growth: abnormal viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	487 total interaction(s) for 285 unique genes/features.
Physical Interactions	Affinity Capture-MS: 2 Affinity Capture-RNA: 1 Affinity Capture-Western: 11 Biochemical Activity: 1 Co-fractionation: 1 Two-hybrid: 39
Genetic Interactions	Dosage Rescue: 1 Negative Genetic: 206 Positive Genetic: 26 Synthetic Growth Defect: 40 Synthetic Lethality: 159
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder | YeastRC Two-Hybrid

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	Organelle DB (UMich) | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP
Homologs	Ashbya (AGD) | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrXIII:856966 to 858087 | ORF Map | GBrowse
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..1122 856966..858087 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000004908