HSH155/YMR288W Summary Help

Standard Name HSH155 1
Systematic Name YMR288W
Feature Type ORF, Verified
Description U2-snRNP associated splicing factor; forms extensive associations with the branch site-3' splice site-3' exon region upon prespliceosome formation; similarity to the mammalian U2 snRNP-associated splicing factor SAP155 (1, 2, 3)
Name Description Human Sap Homolog 1
Chromosomal Location
ChrXIII:845571 to 848486 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All HSH155 GO evidence and references
  View Computational GO annotations for HSH155
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 3 genes
Resources
Classical genetics
conditional
Large-scale survey
conditional
null
reduction of function
Resources
99 total interaction(s) for 60 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 87
  • Affinity Capture-Western: 1
  • Biochemical Activity: 3
  • Co-purification: 1
  • Reconstituted Complex: 1
  • Two-hybrid: 5

Genetic Interactions
  • Synthetic Lethality: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 971
Molecular Weight (Da) 110,027
Isoelectric Point (pI) 7.25
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXIII:845571 to 848486 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..2916 845571..848486 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000004901
References cited on this page View Complete Literature Guide for HSH155
1) Pauling MH, et al.  (2000) Functional Cus1p is found with Hsh155p in a multiprotein splicing factor associated with U2 snRNA. Mol Cell Biol 20(6):2176-85
2) Stevens SW, et al.  (2002) Composition and functional characterization of the yeast spliceosomal penta-snRNP. Mol Cell 9(1):31-44
3) McPheeters DS and Muhlenkamp P  (2003) Spatial organization of protein-RNA interactions in the branch site-3' splice site region during pre-mRNA splicing in yeast. Mol Cell Biol 23(12):4174-86