RRN9/YMR270C Summary

RRN9 BASIC INFORMATION

Standard Name	RRN9 1
Systematic Name	YMR270C
Feature Type	ORF, Verified
Description	Protein involved in promoting high level transcription of rDNA, subunit of UAF (upstream activation factor) for RNA polymerase I (2, 3)
Name Description	Regulation of RNA polymerase I 1

GO Annotations	All RRN9 GO evidence and references
	View Computational GO annotations for RRN9
Molecular Function
Manually curated	rDNA binding (TAS) RNA polymerase I transcription factor activity (TAS)
Biological Process
Manually curated	transcription from RNA polymerase I promoter (TAS) transcription of nuclear rRNA large RNA polymerase I transcript (IGI)
Cellular Component
Manually curated	RNA polymerase I upstream activating factor complex (TAS)

Mutant Phenotype	All RRN9 Phenotype details and references
Classical genetics
conditional	rRNA species transcribed by RNA polymerase I accumulation: decreased heat sensitivity: increased
Large-scale survey
null	inviable
overexpression	vegetative growth: decreased

Interactions	RRN9 All interactions details and references
	21 total interaction(s) for 10 unique genes/features.
Physical Interactions	Affinity Capture-MS: 1 Affinity Capture-RNA: 1 Affinity Capture-Western: 1 Co-purification: 1 Reconstituted Complex: 3 Two-hybrid: 11
Genetic Interactions	Dosage Rescue: 1 Phenotypic Suppression: 1 Synthetic Rescue: 1

Sequence Information

ChrXIII:806422 to 805325 | |

Note: this feature is encoded on the Crick strand.

Last Update

Coordinates: 2004-02-27 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..1098	806422..805325	2004-02-27	1996-07-31

External Links	All Associated Seq \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000004883

RRN9 RESOURCES

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SGD ORF map	GBrowse

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Expression Summary

ADDITIONAL INFORMATION for RRN9

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for RRN9]

1)	Nogi Y, et al. (1991) An approach for isolation of mutants defective in 35S ribosomal RNA synthesis in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 88(16):7026-30
2)	Keys DA, et al. (1996) Multiprotein transcription factor UAF interacts with the upstream element of the yeast RNA polymerase I promoter and forms a stable preinitiation complex. Genes Dev 10(7):887-903
3)	Oakes M, et al. (1999) Transcription factor UAF, expansion and contraction of ribosomal DNA (rDNA) repeats, and RNA polymerase switch in transcription of yeast rDNA. Mol Cell Biol 19(12):8559-69

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