Standard Name	PRP24 1
Systematic Name	YMR268C
Feature Type	ORF, Verified
Description	Splicing factor that reanneals U4 and U6 snRNPs during spliceosome recycling (2)
Name Description	Pre-mRNA Processing 1

Chromosomal Location	ChrXIII:804222 to 802888 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.

	View Computational GO annotations for PRP24
Molecular Function
Manually curated	snRNA binding (IPI) U6 snRNA binding (IDA)
Biological Process
Manually curated	assembly of spliceosomal tri-snRNP (IDA) spliceosomal complex assembly (IMP)
Cellular Component
Manually curated	U6 snRNP (IDA)

Classical genetics
conditional	unspliced intron-containing RNA accumulation: abnormal heat sensitivity: increased
Large-scale survey
null	heat sensitivity: increased inviable
reduction of function	competitive fitness: decreased resistance to methyl methanesulfonate: decreased resistance to sirolimus: decreased
Resources	PROPHECY | PhenoM | SCMD | ScreenTroll | Yeast Fitness Database

	69 total interaction(s) for 33 unique genes/features.
Physical Interactions	Affinity Capture-MS: 27 Affinity Capture-RNA: 8 Affinity Capture-Western: 7 Biochemical Activity: 1 Two-hybrid: 5
Genetic Interactions	Dosage Growth Defect: 2 Negative Genetic: 10 Synthetic Growth Defect: 1 Synthetic Lethality: 7 Synthetic Rescue: 1
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrXIII:804222 to 802888 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..1335 804222..802888 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain M22 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000004881