SAP30/YMR263W Summary Help

SAP30 BASIC INFORMATION

Standard Name SAP30
Systematic Name YMR263W
Feature Type ORF, Verified
Description Subunit of a histone deacetylase complex, along with Rpd3p and Sin3p, that is involved in silencing at telomeres, rDNA, and silent mating-type loci; involved in telomere maintenance (1, 2, 3, 4)
Name Description SIT4 protein phosphatase Associated Protein
GO Annotations All SAP30 GO evidence and references
    View Computational GO annotations for SAP30
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Mutant Phenotype All SAP30 Phenotype details and references
Classical genetics
null
Large-scale survey
null
Interactions SAP30 All interactions details and references
449 total interaction(s) for 248 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 60
  • Affinity Capture-RNA: 1
  • Affinity Capture-Western: 8
  • Two-hybrid: 1
Genetic Interactions
  • Dosage Rescue: 2
  • Phenotypic Enhancement: 178
  • Phenotypic Suppression: 45
  • Synthetic Growth Defect: 61
  • Synthetic Lethality: 88
  • Synthetic Rescue: 5
Sequence Information
ChrXIII:794918 to 795523 | ORF Map | GBrowse
Gbrowse
Last Update Coordinates: 1996-07-31 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..606 794918..795523 1996-07-31 1996-07-31
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000004876

SAP30 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
 GBrowse
  • Literature
  • Retrieve Sequences
  • Sequence Analysis Tools
  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
  • Maps & Displays
  • Comparison Resources
  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

ADDITIONAL INFORMATION for SAP30

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for SAP30]

1) Sun ZW and Hampsey M  (1999) A general requirement for the Sin3-Rpd3 histone deacetylase complex in regulating silencing in Saccharomyces cerevisiae. Genetics 152(3):921-32
2) Zhang Y, et al.  (1998) SAP30, a novel protein conserved between human and yeast, is a component of a histone deacetylase complex. Mol Cell 1(7):1021-31
3) Bernstein BE, et al.  (2000) Genomewide studies of histone deacetylase function in yeast. Proc Natl Acad Sci U S A 97(25):13708-13
4) Askree SH, et al.  (2004) A genome-wide screen for Saccharomyces cerevisiae deletion mutants that affect telomere length. Proc Natl Acad Sci U S A 101(23):8658-63