Standard Name	DFG5
Systematic Name	YMR238W
Feature Type	ORF, Verified
Description	Putative mannosidase, essential glycosylphosphatidylinositol (GPI)-anchored membrane protein required for cell wall biogenesis in bud formation, involved in filamentous growth, homologous to Dcw1p (1, 2, 3)
Name Description	Defective for Filamentous Growth 1

Chromosomal Location	ChrXIII:746353 to 747729 | ORF Map | GBrowse

	View Computational GO annotations for DFG5
Molecular Function
Manually curated	molecular_function unknown (ND)
Biological Process
Manually curated	budding cell bud growth (IGI) fungal-type cell wall biogenesis (IDA) pseudohyphal growth (IMP)
Cellular Component
Manually curated	anchored to plasma membrane (ISA)
High-throughput	endoplasmic reticulum (IDA)

Classical genetics
unspecified	pseudohyphal growth: decreased pseudohyphal growth: absent
Large-scale survey
null	competitive fitness: decreased resistance to cycloheximide: decreased resistance to wortmannin: increased resistance to sirolimus: decreased resistance to oleate: decreased resistance to neomycin: decreased resistance to chloroquine: decreased resistance to neothyonidioside: decreased sporulation: decreased starvation resistance: decreased stress resistance: decreased vegetative growth: abnormal vegetative growth: decreased rate viable
overexpression	vegetative growth: decreased rate
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	33 total interaction(s) for 32 unique genes/features.
Physical Interactions	Affinity Capture-MS: 6 Affinity Capture-RNA: 1 Biochemical Activity: 1 PCA: 2 Two-hybrid: 1
Genetic Interactions	Dosage Lethality: 1 Negative Genetic: 12 Phenotypic Suppression: 3 Positive Genetic: 2 Synthetic Growth Defect: 2 Synthetic Lethality: 1 Synthetic Rescue: 1
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder | YeastRC Two-Hybrid

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrXIII:746353 to 747729 | ORF Map | GBrowse
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..1377 746353..747729 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CEN.PK113-7D S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain M22 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000004851