DFG5/YMR238W Summary

DFG5 BASIC INFORMATION

Standard Name	DFG5
Systematic Name	YMR238W
Feature Type	ORF, Verified
Description	Putative mannosidase, essential glycosylphosphatidylinositol (GPI)-anchored membrane protein required for cell wall biogenesis in bud formation, involved in filamentous growth, homologous to Dcw1p (1, 2, 3)
Name Description	Defective for Filamentous Growth 1

GO Annotations	All DFG5 GO evidence and references
	View Computational GO annotations for DFG5
Molecular Function
Manually curated	mannosidase activity (ISS)
Biological Process
Manually curated	budding cell bud growth (IGI) fungal-type cell wall biogenesis (IDA) pseudohyphal growth (IMP)
Cellular Component
Manually curated	anchored to plasma membrane (IDA)

Mutant Phenotype	All DFG5 Phenotype details and references
Classical genetics
unspecified	pseudohyphal growth: absent pseudohyphal growth: decreased
Large-scale survey
null	competitive fitness: decreased resistance to rapamycin: decreased resistance to wortmannin: increased resistance to oleate: decreased sporulation: decreased viable

Interactions	DFG5 All interactions details and references
	9 total interaction(s) for 9 unique genes/features.
Physical Interactions	Biochemical Activity: 1 PCA: 2 Two-hybrid: 1
Genetic Interactions	Phenotypic Suppression: 3 Synthetic Lethality: 2

Sequence Information

ChrXIII:746352 to 747728 | |

Last Update

Coordinates: 1996-07-31 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..1377	746352..747728	1996-07-31	1996-07-31

External Links	All Associated Seq \| E.C. \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000004851

DFG5 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for DFG5

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for DFG5]

1)	Mosch HU and Fink GR (1997) Dissection of filamentous growth by transposon mutagenesis in Saccharomyces cerevisiae. Genetics 145(3):671-84
2)	Kitagaki H, et al. (2002) Two homologous genes, DCW1 (YKL046c) and DFG5, are essential for cell growth and encode glycosylphosphatidylinositol (GPI)-anchored membrane proteins required for cell wall biogenesis in Saccharomyces cerevisiae. Mol Microbiol 46(4):1011-22
3)	Kitagaki H, et al. (2004) A temperature-sensitive dcw1 mutant of Saccharomyces cerevisiae is cell cycle arrested with small buds which have aberrant cell walls. Eukaryot Cell 3(5):1297-306

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