RNA1/YMR235C Summary Help

Standard Name RNA1
Systematic Name YMR235C
Feature Type ORF, Verified
Description GTPase activating protein (GAP) for Gsp1p; involved in nuclear transport (1, 2)
Name Description RaN GTPase Activating protein
Chromosomal Location
ChrXIII:742735 to 741512 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Genetic position: 159 cM
Gene Ontology Annotations All RNA1 GO evidence and references
  View Computational GO annotations for RNA1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 4 genes
Resources
Classical genetics
conditional
null
repressible
Large-scale survey
conditional
null
overexpression
reduction of function
repressible
Resources
169 total interaction(s) for 147 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 25
  • Affinity Capture-RNA: 3
  • Affinity Capture-Western: 3
  • Biochemical Activity: 3
  • Co-purification: 1
  • PCA: 1
  • Reconstituted Complex: 7
  • Two-hybrid: 25

Genetic Interactions
  • Dosage Lethality: 2
  • Dosage Rescue: 4
  • Negative Genetic: 71
  • Phenotypic Enhancement: 1
  • Positive Genetic: 9
  • Synthetic Growth Defect: 1
  • Synthetic Lethality: 8
  • Synthetic Rescue: 5

Resources
Expression Summary
histogram
Resources
Length (a.a.) 407
Molecular Weight (Da) 45,815
Isoelectric Point (pI) 4.36
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXIII:742735 to 741512 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Genetic position: 159 cM
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1224 742735..741512 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000004848
References cited on this page View Complete Literature Guide for RNA1
1) Becker J, et al.  (1995) RNA1 encodes a GTPase-activating protein specific for Gsp1p, the Ran/TC4 homologue of Saccharomyces cerevisiae. J Biol Chem 270(20):11860-5
2) Ryan KJ, et al.  (2003) The Ran GTPase cycle is required for yeast nuclear pore complex assembly. J Cell Biol 160(7):1041-53