Standard Name	RNH1
Systematic Name	YMR234W
Feature Type	ORF, Verified
Description	Ribonuclease H1; able to bind double-stranded RNAs and RNA-DNA hybrids; associates with RNAse polymerase I; the homolog of mammalian RNAse HII (the S. cerevisiae homolog of mammalian RNAse HI is RNH201) (1, 2, 3)
Name Description	RNase H

Chromosomal Location	ChrXIII:740266 to 741312 | ORF Map | GBrowse
	Genetic position: 160 cM

	View Computational GO annotations for RNH1
Molecular Function
Manually curated	ribonuclease H activity (IDA)
Biological Process
Manually curated	RNA catabolic process (IDA)
Cellular Component
Manually curated	intracellular (TAS) nucleus (IC)

Classical genetics
unspecified	resistance to papulacandin B: decreased resistance to hygromycin B: decreased resistance to caffeine: decreased
Large-scale survey
null	competitive fitness: decreased haploinsufficient resistance to tirapazamine: increased resistance to arsenite(3-): decreased viable
unspecified	resistance to Calcofluor White: decreased
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	57 total interaction(s) for 46 unique genes/features.
Physical Interactions	Affinity Capture-MS: 4
Genetic Interactions	Dosage Rescue: 1 Negative Genetic: 6 Phenotypic Enhancement: 4 Phenotypic Suppression: 22 Positive Genetic: 1 Synthetic Growth Defect: 7 Synthetic Lethality: 10 Synthetic Rescue: 2
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrXIII:740266 to 741312 | ORF Map | GBrowse
	Genetic position: 160 cM
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..1047 740266..741312 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain M22 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain Y10 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000004847