ICY1/YMR195W Summary Help

Standard Name ICY1
Systematic Name YMR195W
Feature Type ORF, Verified
Description Protein of unknown function; required for viability in rich media of cells lacking mitochondrial DNA; mutants have an invasive growth defect with elongated morphology; induced by amino acid starvation; ICY1 has a paralog, ICY2, that arose from the whole genome duplication (1, 2, 3, 4)
Name Description Interacting with the CYtoskeleton
Chromosomal Location
ChrXIII:654034 to 654417 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All ICY1 GO evidence and references
  View Computational GO annotations for ICY1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
High-throughput
Regulators 143 genes
Resources
Classical genetics
null
overexpression
Large-scale survey
null
overexpression
Resources
8 total interaction(s) for 8 unique genes/features.
Physical Interactions
  • Affinity Capture-RNA: 3

Genetic Interactions
  • Dosage Lethality: 1
  • Dosage Rescue: 1
  • Negative Genetic: 1
  • Synthetic Growth Defect: 1
  • Synthetic Rescue: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 127
Molecular Weight (Da) 14,336
Isoelectric Point (pI) 4.4
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXIII:654034 to 654417 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..384 654034..654417 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000004808
References cited on this page View Complete Literature Guide for ICY1
1) Suzuki C, et al.  (2003) Screening and characterization of transposon-insertion mutants in a pseudohyphal strain of Saccharomyces cerevisiae. Yeast 20(5):407-15
2) Dunn CD and Jensen RE  (2003) Suppression of a defect in mitochondrial protein import identifies cytosolic proteins required for viability of yeast cells lacking mitochondrial DNA. Genetics 165(1):35-45
3) Kleinschmidt M, et al.  (2005) Transcriptional profiling of Saccharomyces cerevisiae cells under adhesion-inducing conditions. Mol Genet Genomics 273(5):382-93
4) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61