GYL1/YMR192W Summary Help

GYL1 BASIC INFORMATION

Standard Name GYL1 1
Systematic Name YMR192W
Alias APP2 2
Feature Type ORF, Verified
Description Putative GTPase activating protein (GAP) that may have a role in polarized exocytosis; stimulates Gyp5p GAP activity on Ypt1p, colocalizes with Gyp5p at sites of polarized growth; interacts with Gyp5p, Rvs161p, and Rvs167p (1, 2, 3, 4)
Name Description GYp Like 2
GO Annotations All GYL1 GO evidence and references
    View Computational GO annotations for GYL1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Mutant Phenotype All GYL1 Phenotype details and references
Large-scale survey
null
Interactions GYL1 All interactions details and references
42 total interaction(s) for 16 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 10
  • Affinity Capture-RNA: 1
  • Affinity Capture-Western: 2
  • Biochemical Activity: 1
  • Co-fractionation: 1
  • Co-localization: 1
  • Far Western: 2
  • PCA: 3
  • Protein-peptide: 4
  • Reconstituted Complex: 2
  • Two-hybrid: 14

Genetic Interactions
  • Phenotypic Enhancement: 1

Sequence Information
ChrXIII:647117 to 649279 | ORF Map | GBrowse
Gbrowse
Last Update Coordinates: 1996-07-31 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..2163 647117..649279 1996-07-31 1996-07-31
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000004804

GYL1 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
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  • Localization Resources
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  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for GYL1]

1) Chesneau L, et al.  (2004) Gyp5p and Gyl1p are involved in the control of polarized exocytosis in budding yeast. J Cell Sci 117(Pt 20):4757-67
2) Samanta MP and Liang S  (2003) Predicting protein functions from redundancies in large-scale protein interaction networks. Proc Natl Acad Sci U S A 100(22):12579-83
3) Bon E, et al.  (2000) A network of proteins around Rvs167p and Rvs161p, two proteins related to the yeast actin cytoskeleton. Yeast 16(13):1229-41
4) Friesen H, et al.  (2005) Interaction of the Saccharomyces cerevisiae cortical actin patch protein Rvs167p with proteins involved in ER to Golgi vesicle trafficking. Genetics 170(2):555-68