SPG5/YMR191W Summary Help

Standard Name SPG5 1
Systematic Name YMR191W
Feature Type ORF, Verified
Description Protein required for proteasome assembly during quiescence; binds to base of the proteasome regulartory particle; required for survival at high temperature during stationary phase; not required for growth on nonfermentable carbon sources (1, 2)
Name Description Stationary Phase Gene 1
Chromosomal Location
ChrXIII:645656 to 646777 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All SPG5 GO evidence and references
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 8 genes
Resources
Classical genetics
null
Large-scale survey
null
Resources
25 total interaction(s) for 21 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 23

Genetic Interactions
  • Negative Genetic: 1
  • Synthetic Growth Defect: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 373
Molecular Weight (Da) 42,163
Isoelectric Point (pI) 10.29
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXIII:645656 to 646777 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 2003-09-22
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1122 645656..646777 2011-02-03 2003-09-22
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000004803
References cited on this page View Complete Literature Guide for SPG5
1) Martinez MJ, et al.  (2004) Genomic analysis of stationary-phase and exit in Saccharomyces cerevisiae: gene expression and identification of novel essential genes. Mol Biol Cell 15(12):5295-305
2) Hanna J, et al.  (2012) Spg5 protein regulates the proteasome in quiescence. J Biol Chem 287(41):34400-9