PSO2/YMR137C Summary Help

PSO2 BASIC INFORMATION

Standard Name PSO2 1
Systematic Name YMR137C
Alias SNM1 2
Feature Type ORF, Verified
Description Required for a post-incision step in the repair of DNA single and double-strand breaks that result from interstrand crosslinks produced by a variety of mono- and bi-functional psoralen derivatives; induced by UV-irradiation (3, 4, 5, 6, 7, 8)
Name Description PSOralen derivative sensitive 1
GO Annotations All PSO2 GO evidence and references
    View Computational GO annotations for PSO2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Mutant Phenotype All PSO2 Phenotype details and references
Classical genetics
null
unspecified
Large-scale survey
null
Interactions PSO2 All interactions details and references
25 total interaction(s) for 18 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 3
Genetic Interactions
  • Phenotypic Enhancement: 18
  • Phenotypic Suppression: 4
Sequence Information
ChrXIII:544962 to 542977 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Last Update Coordinates: 1996-07-31 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..1986 544962..542977 1996-07-31 1996-07-31
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000004745

PSO2 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
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  • Sequence Analysis Tools
  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
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  • Comparison Resources
  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

ADDITIONAL INFORMATION for PSO2

NOMENCLATURE CONFLICT NOTE

NameRelevanceDescription
SNM1Nomenclature conflictSNM1 has been used to refer to both PSO2/YMR137C, which encodes a protein involved in DNA repair, and SNM1/YDR478W, which encodes a subunit of RNase MRP.

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for PSO2]

1) Henriques JA and Moustacchi E  (1980) Isolation and characterization of pso mutants sensitive to photo-addition of psoralen derivatives in Saccharomyces cerevisiae. Genetics 95(2):273-88
2) Cassier-Chauvat C and Moustacchi E  (1988) Allelism between pso1-1 and rev3-1 mutants and between pso2-1 and snm1 mutants in Saccharomyces cerevisiae. Curr Genet 13(1):37-40
3) Cassier C and Moustacchi E  (1981) Mutagenesis induced by mono- and bi-functional alkylating agents in yeast mutants sensitive to photo-addition of furocoumarins (pso). Mutat Res 84(1):37-47
4) Wilborn F and Brendel M  (1989) Formation and stability of interstrand cross-links induced by cis- and trans-diamminedichloroplatinum (II) in the DNA of Saccharomyces cerevisiae strains differing in repair capacity. Curr Genet 16(5-6):331-8
5) Angulo JF, et al.  (1986) Induction of polypeptides in Saccharomyces cerevisiae after ultraviolet irradiation. Biochem Biophys Res Commun 138(2):679-86
6) Magana-Schwencke N, et al.  (1982) The fate of 8-methoxypsoralen photoinduced crosslinks in nuclear and mitochondrial yeast DNA: comparison of wild-type and repair-deficient strains. Proc Natl Acad Sci U S A 79(6):1722-6
7) Li X and Moses RE  (2003) The beta-lactamase motif in Snm1 is required for repair of DNA double-strand breaks caused by interstrand crosslinks in S. cerevisiae. DNA Repair (Amst) 2(1):121-9
8) Brendel M, et al.  (2003) Role of PSO genes in repair of DNA damage of Saccharomyces cerevisiae. Mutat Res 544(2-3):179-93