Standard Name	RIM9 1
Systematic Name	YMR063W
Feature Type	ORF, Verified
Description	Plasma membrane protein of unknown function; involved in the proteolytic activation of Rim101p in response to alkaline pH; interacts with Rim21p and Dfg16p to form a pH-sensing complex in the Rim101 pathway and is required to maintain Rim21p levels; has similarity to A. nidulans PalI; (2, 3, 4)
Name Description	Regulator of IME2 1

Chromosomal Location	ChrXIII:397077 to 397796 | ORF Map | GBrowse

	View Computational GO annotations for RIM9
Molecular Function
Manually curated	molecular_function unknown (ND)
Biological Process
Manually curated	ascospore formation (IMP)
Cellular Component
Manually curated	plasma membrane (IDA)
High-throughput	integral to membrane (ISM)

Classical genetics
conditional	cold sensitivity: increased
null	biofilm formation: decreased invasive growth: decreased Rim21p accumulation: decreased Dfg16p accumulation: decreased Rim21p distribution: abnormal Dfg16p distribution: abnormal
unspecified	sporulation efficiency: decreased
Large-scale survey
null	cell cycle progression in G1 phase: increased duration competitive fitness: decreased endocytosis: decreased filamentous growth: decreased haploproficient heat sensitivity: increased hyperosmotic stress resistance: decreased invasive growth: absent mitochondrial morphology: abnormal Rad52-YFP distribution: increased resistance to dihydromotuporamine C: decreased resistance to sirolimus: decreased resistance to BPS: decreased resistance to ethanol: decreased resistance to lovastatin: decreased resistance to wortmannin: normal resistance to fluconazole: decreased resistance to calcium dichloride: decreased resistance to tunicamycin: decreased resistance to pyrrolidine dithiocarbamate: decreased resistance to hydrogen chloride: increased respiratory growth: decreased rate sporulation efficiency: decreased stress resistance: increased toxin resistance: decreased utilization of carbon source: decreased viable
overexpression	filamentous growth: increased vegetative growth: decreased rate
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	170 total interaction(s) for 124 unique genes/features.
Physical Interactions	Affinity Capture-Western: 2
Genetic Interactions	Dosage Growth Defect: 1 Dosage Rescue: 1 Negative Genetic: 133 Phenotypic Enhancement: 1 Phenotypic Suppression: 1 Positive Genetic: 16 Synthetic Growth Defect: 9 Synthetic Lethality: 3 Synthetic Rescue: 3
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	Organelle DB (UMich) | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | AspGD Homologs | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrXIII:397077 to 397796 | ORF Map | GBrowse
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..720 397077..397796 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000004667