HXT2/YMR011W Summary

HXT2 BASIC INFORMATION

Standard Name	HXT2
Systematic Name	YMR011W
Feature Type	ORF, Verified
Description	High-affinity glucose transporter of the major facilitator superfamily, expression is induced by low levels of glucose and repressed by high levels of glucose (1, 2)
Name Description	HeXose Transporter

GO Annotations	All HXT2 GO evidence and references
	View Computational GO annotations for HXT2
Molecular Function
Manually curated	fructose transmembrane transporter activity (TAS) glucose transmembrane transporter activity (IDA, TAS) mannose transmembrane transporter activity (TAS) pentose transmembrane transporter activity (IMP)
Biological Process
Manually curated	glucose transport (IMP)
Cellular Component
Manually curated	membrane fraction (IDA) plasma membrane (IDA)

Mutant Phenotype	All HXT2 Phenotype details and references
Classical genetics
null	colony size: decreased growth in exponential phase: normal rate resistance to quinine: increased small molecule transport: decreased viable
Large-scale survey
null	UV resistance: decreased resistance to methyl methanesulfonate: decreased viable

Interactions	HXT2 All interactions details and references
	23 total interaction(s) for 21 unique genes/features.
Physical Interactions	Affinity Capture-RNA: 1 Co-fractionation: 2 PCA: 6 Two-hybrid: 2
Genetic Interactions	Dosage Rescue: 4 Phenotypic Enhancement: 7 Synthetic Rescue: 1

Sequence Information

ChrXIII:288078 to 289703 | |

Last Update

Coordinates: 1996-07-31 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..1626	288078..289703	1996-07-31	1996-07-31

External Links	All Associated Seq \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| TCDB \| UniProtKB

Primary SGDID	S000004613

HXT2 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for HXT2

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for HXT2]

1)	Ozcan S and Johnston M (1999) Function and regulation of yeast hexose transporters. Microbiol Mol Biol Rev 63(3):554-69
2)	Ozcan S and Johnston M (1995) Three different regulatory mechanisms enable yeast hexose transporter (HXT) genes to be induced by different levels of glucose. Mol Cell Biol 15(3):1564-72

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