COS3/YML132W Summary Help

Standard Name COS3
Systematic Name YML132W
Feature Type ORF, Verified
Description Protein involved in salt resistance; interacts with sodium:hydrogen antiporter Nha1p; member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins (1, 2)
Name Description COnserved Sequence
Chromosomal Location
ChrXIII:7244 to 8383 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All COS3 GO evidence and references
  View Computational GO annotations for COS3
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 4 genes
Resources
Classical genetics
null
overexpression
Large-scale survey
overexpression
Resources
13 total interaction(s) for 12 unique genes/features.
Physical Interactions
  • Affinity Capture-RNA: 1
  • Affinity Capture-Western: 1
  • Co-fractionation: 1
  • PCA: 8

Genetic Interactions
  • Positive Genetic: 1
  • Synthetic Rescue: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 379
Molecular Weight (Da) 45,165
Isoelectric Point (pI) 8.64
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXIII:7244 to 8383 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 1996-07-31 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1140 7244..8383 1996-07-31 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000004601
References cited on this page View Complete Literature Guide for COS3
1) Spode I, et al.  (2002) ATF/CREB sites present in sub-telomeric regions of Saccharomyces cerevisiae chromosomes are part of promoters and act as UAS/URS of highly conserved COS genes. J Mol Biol 319(2):407-20
2) Despons L, et al.  (2006) An evolutionary scenario for one of the largest yeast gene families. Trends Genet 22(1):10-5