PRE8/YML092C Summary

PRE8 BASIC INFORMATION

Standard Name	PRE8
Systematic Name	YML092C
Feature Type	ORF, Verified
Description	Alpha 2 subunit of the 20S proteasome (1)
Name Description	PRoteinase yscE

GO Annotations	All PRE8 GO evidence and references
	View Computational GO annotations for PRE8
Molecular Function
Manually curated	endopeptidase activity (TAS)
Biological Process
Manually curated	ubiquitin-dependent protein catabolic process (TAS)
Cellular Component
Manually curated	proteasome core complex, alpha-subunit complex (IPI, TAS) proteasome storage granule (IDA)

Mutant Phenotype	All PRE8 Phenotype details and references
Large-scale survey
conditional	heat sensitivity: increased
null	inviable

Interactions	PRE8 All interactions details and references
	140 total interaction(s) for 46 unique genes/features.
Physical Interactions	Affinity Capture-MS: 71 Affinity Capture-RNA: 2 Affinity Capture-Western: 12 Co-purification: 1 PCA: 2 Two-hybrid: 4
Genetic Interactions	Dosage Rescue: 2 Synthetic Growth Defect: 18 Synthetic Rescue: 28

Sequence Information

ChrXIII:86739 to 85987 | |

Note: this feature is encoded on the Crick strand.

Last Update

Coordinates: 1996-07-31 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..753	86739..85987	1996-07-31	1996-07-31

External Links	All Associated Seq \| E.C. \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000004557

PRE8 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for PRE8

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for PRE8]

1)	Hochstrasser M (1996) Ubiquitin-dependent protein degradation. Annu Rev Genet 30:405-39

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