Standard Name	BET5 1
Systematic Name	YML077W
Feature Type	ORF, Verified
Description	Component of the TRAPP (transport protein particle) complex, which plays an essential role in the vesicular transport from endoplasmic reticulum to Golgi (2)
Name Description	Blocked Early in Transport 3

Chromosomal Location	ChrXIII:111865 to 112344 | ORF Map | GBrowse

	View Computational GO annotations for BET5
Molecular Function
Manually curated	contributes_to Rab guanyl-nucleotide exchange factor activity (IDA, IGI, IMP)
Biological Process
Manually curated	ER to Golgi vesicle-mediated transport (IGI, IMP)
Cellular Component
Manually curated	TRAPP complex (IDA)

Classical genetics
conditional	endomembrane system morphology: abnormal endoplasmic reticulum morphology: abnormal heat sensitivity: increased alpha factor secretion: absent carboxypeptidase Y (CPY) transport: decreased
null	inviable
repressible	alpha factor secretion: absent carboxypeptidase Y (CPY) transport: decreased
Large-scale survey
conditional	colony sectoring: increased heat sensitivity: increased
null	haploinsufficient inviable starvation resistance: decreased
reduction of function	competitive fitness: decreased
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	79 total interaction(s) for 40 unique genes/features.
Physical Interactions	Affinity Capture-MS: 17 Affinity Capture-RNA: 2 Affinity Capture-Western: 15 Co-fractionation: 1 Co-purification: 1 Reconstituted Complex: 2 Two-hybrid: 8
Genetic Interactions	Dosage Rescue: 12 Negative Genetic: 14 Positive Genetic: 1 Synthetic Growth Defect: 1 Synthetic Lethality: 4 Synthetic Rescue: 1
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP
Homologs	Ashbya (AGD) | AspGD Homologs | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrXIII:111865 to 112344 | ORF Map | GBrowse
Last Update	Coordinates: 1996-07-31 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..480 111865..112344 1996-07-31 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain M22 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain Y10 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000004542