ERV41/YML067C Summary Help

Standard Name ERV41
Systematic Name YML067C
Feature Type ORF, Verified
Description Protein localized to COPII-coated vesicles; forms a complex with Erv46p; involved in the membrane fusion stage of transport; has homology to human ERGIC2 (PTX1) protein (1, 2)
Name Description ER Vesicle
Chromosomal Location
ChrXIII:140214 to 139063 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All ERV41 GO evidence and references
  View Computational GO annotations for ERV41
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 3 genes
Resources
Classical genetics
null
Large-scale survey
null
overexpression
Resources
161 total interaction(s) for 111 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 20
  • Affinity Capture-Western: 7
  • Co-fractionation: 1
  • Co-purification: 1
  • PCA: 21
  • Two-hybrid: 1

Genetic Interactions
  • Negative Genetic: 78
  • Phenotypic Suppression: 10
  • Positive Genetic: 17
  • Synthetic Growth Defect: 2
  • Synthetic Lethality: 3

Resources
Expression Summary
histogram
Resources
Length (a.a.) 352
Molecular Weight (Da) 40,705
Isoelectric Point (pI) 4.59
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXIII:140214 to 139063 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 1996-07-31 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..31 140214..140184 1996-07-31 1996-07-31
Intron 32..124 140183..140091 1996-07-31 1996-07-31
CDS 125..1152 140090..139063 1996-07-31 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000004532
References cited on this page View Complete Literature Guide for ERV41
1) Otte S, et al.  (2001) Erv41p and Erv46p: new components of COPII vesicles involved in transport between the ER and Golgi complex. J Cell Biol 152(3):503-18
2) Kwok SC, et al.  (2006) PTX1(ERGIC2)-VP22 fusion protein upregulates interferon-beta in prostate cancer cell line PC-3. DNA Cell Biol 25(9):523-9