Standard Name	CYB2 1
Systematic Name	YML054C
Alias	FCB2
Feature Type	ORF, Verified
Description	Cytochrome b2 (L-lactate cytochrome-c oxidoreductase), component of the mitochondrial intermembrane space, required for lactate utilization; expression is repressed by glucose and anaerobic conditions (2, 3)
Name Description	CYtochrome B

Chromosomal Location	ChrXIII:167308 to 165533 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
	Genetic position: -30 cM

	View Computational GO annotations for CYB2
Molecular Function
Manually curated	L-lactate dehydrogenase (cytochrome) activity (IDA)
Biological Process
Manually curated	lactate metabolic process (IMP)
Cellular Component
Manually curated	mitochondrial intermembrane space (IDA) mitochondrion (IDA)
High-throughput	mitochondrion (IDA)

Classical genetics
null	utilization of carbon source: absent
unspecified	utilization of carbon source: absent
Large-scale survey
null	competitive fitness: increased vacuolar morphology: abnormal viable
overexpression	vegetative growth: decreased rate
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	29 total interaction(s) for 28 unique genes/features.
Physical Interactions	Affinity Capture-RNA: 3 Affinity Capture-Western: 6 Biochemical Activity: 1 Protein-peptide: 1 Reconstituted Complex: 1
Genetic Interactions	Negative Genetic: 10 Positive Genetic: 6 Synthetic Rescue: 1
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	Organelle DB (UMich) | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | AspGD Homologs | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrXIII:167308 to 165533 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
	Genetic position: -30 cM
Last Update	Coordinates: 1996-07-31 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..1776 167308..165533 1996-07-31 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain Y10 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000004518