CYB2/YML054C Summary Help

Standard Name CYB2 1
Systematic Name YML054C
Alias FCB2
Feature Type ORF, Verified
Description Cytochrome b2 (L-lactate cytochrome-c oxidoreductase); component of the mitochondrial intermembrane space, required for lactate utilization; expression is repressed by glucose and anaerobic conditions (2, 3)
Name Description CYtochrome B
Chromosomal Location
ChrXIII:167308 to 165533 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Genetic position: -30 cM
Gene Ontology Annotations All CYB2 GO evidence and references
  View Computational GO annotations for CYB2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 8 genes
Resources
Classical genetics
null
unspecified
Large-scale survey
null
overexpression
Resources
30 total interaction(s) for 29 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 1
  • Affinity Capture-RNA: 3
  • Affinity Capture-Western: 6
  • Biochemical Activity: 1
  • Protein-peptide: 1
  • Reconstituted Complex: 1

Genetic Interactions
  • Negative Genetic: 10
  • Positive Genetic: 6
  • Synthetic Rescue: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 591
Molecular Weight (Da) 65,539
Isoelectric Point (pI) 8.56
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXIII:167308 to 165533 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Genetic position: -30 cM
Last Update Coordinates: 1996-07-31 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1776 167308..165533 1996-07-31 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000004518
References cited on this page View Complete Literature Guide for CYB2
1) Lodi, T., et al.  (1989) Personal Communication, Mortimer Map Edition 10
2) Lodi T and Guiard B  (1991) Complex transcriptional regulation of the Saccharomyces cerevisiae CYB2 gene encoding cytochrome b2: CYP1(HAP1) activator binds to the CYB2 upstream activation site UAS1-B2. Mol Cell Biol 11(7):3762-72
3) Guiard B  (1985) Structure, expression and regulation of a nuclear gene encoding a mitochondrial protein: the yeast L(+)-lactate cytochrome c oxidoreductase (cytochrome b2). EMBO J 4(12):3265-72