RSE1/YML049C Summary

RSE1 BASIC INFORMATION

Standard Name	RSE1
Systematic Name	YML049C
Feature Type	ORF, Verified
Description	Protein involved in pre-mRNA splicing; component of the pre-spliceosome; associates with U2 snRNA; involved in ER to Golgi transport (1, 2)
Name Description	RNA Splicing and ER to Golgi transport

GO Annotations	All RSE1 GO evidence and references
	View Computational GO annotations for RSE1
Molecular Function
Manually curated	U2 snRNA binding (IPI)
Biological Process
Manually curated	nuclear mRNA splicing, via spliceosome (IGI, IMP, IPI) spliceosome assembly (IDA)
Cellular Component
Manually curated	colocalizes_with U2 snRNP (IDA) U2 snRNP (IDA, IPI) U2-type prespliceosome (IDA)

Mutant Phenotype	All RSE1 Phenotype details and references
Large-scale survey
null	inviable

Interactions	RSE1 All interactions details and references
	103 total interaction(s) for 56 unique genes/features.
Physical Interactions	Affinity Capture-MS: 97 Affinity Capture-RNA: 2 Co-purification: 1 Two-hybrid: 2
Genetic Interactions	Dosage Rescue: 1

Sequence Information

ChrXIII:178305 to 174220 | |

Note: this feature is encoded on the Crick strand.

Last Update

Coordinates: 1996-07-31 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..4086	178305..174220	1996-07-31	1996-07-31

External Links	All Associated Seq \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000004513

RSE1 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for RSE1

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for RSE1]

1)	Caspary F, et al. (1999) Partial purification of the yeast U2 snRNP reveals a novel yeast pre-mRNA splicing factor required for pre-spliceosome assembly. EMBO J 18(12):3463-74
2)	Chen EJ, et al. (1998) A link between secretion and pre-mRNA processing defects in Saccharomyces cerevisiae and the identification of a novel splicing gene, RSE1. Mol Cell Biol 18(12):7139-46

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