GSF2/YML048W Summary Help

Standard Name GSF2 1
Systematic Name YML048W
Alias ECM6
Feature Type ORF, Verified
Description Endoplasmic reticulum (ER) localized integral membrane protein; may promote secretion of certain hexose transporters, including Gal2p; involved in glucose-dependent repression (1, 2)
Name Description Glucose Signaling Factor 1
Chromosomal Location
ChrXIII:178426 to 179637 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All GSF2 GO evidence and references
  View Computational GO annotations for GSF2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 7 genes
Resources
Classical genetics
null
unspecified
Large-scale survey
null
overexpression
unspecified
Resources
213 total interaction(s) for 163 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 18
  • Affinity Capture-RNA: 2
  • Biochemical Activity: 4
  • Co-purification: 1
  • PCA: 60
  • Protein-peptide: 3
  • Reconstituted Complex: 10

Genetic Interactions
  • Dosage Rescue: 1
  • Negative Genetic: 79
  • Positive Genetic: 30
  • Synthetic Growth Defect: 5

Resources
Expression Summary
histogram
Resources
Length (a.a.) 403
Molecular Weight (Da) 45,869
Isoelectric Point (pI) 7.14
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXIII:178426 to 179637 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 1996-07-31 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1212 178426..179637 1996-07-31 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000004511
References cited on this page View Complete Literature Guide for GSF2
1) Sherwood PW and Carlson M  (1997) Mutations in GSF1 and GSF2 alter glucose signaling in Saccharomyces cerevisiae. Genetics 147(2):557-66
2) Sherwood PW and Carlson M  (1999) Efficient export of the glucose transporter Hxt1p from the endoplasmic reticulum requires Gsf2p. Proc Natl Acad Sci U S A 96(13):7415-20