RRN11/YML043C Summary

RRN11 BASIC INFORMATION

Standard Name	RRN11 1
Systematic Name	YML043C
Feature Type	ORF, Verified
Description	Component of the core factor (CF) rDNA transcription factor complex; CF is required for transcription of 35S rRNA genes by RNA polymerase I and is composed of Rrn6p, Rrn7p, and Rrn11p (1, 2, 3, 4)
Name Description	Regulation of RNA polymerase I

GO Annotations	All RRN11 GO evidence and references
	View Computational GO annotations for RRN11
Molecular Function
Manually curated	promoter binding (NAS) RNA polymerase I transcription factor activity (IDA, IGI, IMP)
Biological Process
Manually curated	transcription from RNA polymerase I promoter (IDA) transcription initiation from RNA polymerase I promoter (NAS) transcription of nuclear rRNA large RNA polymerase I transcript (IGI, IMP)
Cellular Component
Manually curated	RNA polymerase I core factor complex (IDA)

Mutant Phenotype	All RRN11 Phenotype details and references
Large-scale survey
null	inviable
repressible	cell cycle progression in G1 phase: abnormal

Interactions	RRN11 All interactions details and references
	16 total interaction(s) for 10 unique genes/features.
Physical Interactions	Affinity Capture-MS: 1 Affinity Capture-Western: 6 Protein-RNA: 1 Two-hybrid: 4
Genetic Interactions	Synthetic Lethality: 4

Sequence Information

ChrXIII:191767 to 190244 | |

Note: this feature is encoded on the Crick strand.

Last Update

Coordinates: 1996-07-31 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..1524	191767..190244	1996-07-31	1996-07-31

External Links	All Associated Seq \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000004507

RRN11 RESOURCES

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SGD ORF map	GBrowse

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Expression Summary

ADDITIONAL INFORMATION for RRN11

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for RRN11]

1)	Lalo D, et al. (1996) RRN11 encodes the third subunit of the complex containing Rrn6p and Rrn7p that is essential for the initiation of rDNA transcription by yeast RNA polymerase I. J Biol Chem 271(35):21062-7
2)	Steffan JS, et al. (1996) The role of TBP in rDNA transcription by RNA polymerase I in Saccharomyces cerevisiae: TBP is required for upstream activation factor-dependent recruitment of core factor. Genes Dev 10(20):2551-63
3)	Lin CW, et al. (1996) A novel 66-kilodalton protein complexes with Rrn6, Rrn7, and TATA-binding protein to promote polymerase I transcription initiation in Saccharomyces cerevisiae. Mol Cell Biol 16(11):6436-43
4)	Keener J, et al. (1998) Reconstitution of yeast RNA polymerase I transcription in vitro from purified components. TATA-binding protein is not required for basal transcription. J Biol Chem 273(50):33795-802

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