NDC1/YML031W Summary Help

NDC1 BASIC INFORMATION

Standard Name NDC1 1
Systematic Name YML031W
Feature Type ORF, Verified
Description Nuclear envelope protein with multiple putative transmembrane domains, required for nuclear pore complex assembly and spindle pole body duplication; required for meiosis II (2, 3, 4)
Name Description Nuclear Division Cycle
GO Annotations All NDC1 GO evidence and references
    View Computational GO annotations for NDC1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Mutant Phenotype All NDC1 Phenotype details and references
Large-scale survey
null
overexpression
Interactions NDC1 All interactions details and references
47 total interaction(s) for 32 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 11
  • Affinity Capture-Western: 1
  • Biochemical Activity: 1
  • Co-fractionation: 1
  • Co-purification: 1
  • PCA: 5
  • Reconstituted Complex: 3
  • Two-hybrid: 5
Genetic Interactions
  • Dosage Rescue: 4
  • Phenotypic Enhancement: 1
  • Phenotypic Suppression: 1
  • Synthetic Growth Defect: 5
  • Synthetic Lethality: 2
  • Synthetic Rescue: 6
Sequence Information
ChrXIII:214189 to 216156 | ORF Map | GBrowse
Gbrowse
Genetic position: -18 cM
Last Update Coordinates: 1996-07-31 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..1968 214189..216156 1996-07-31 1996-07-31
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000004493

NDC1 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
 GBrowse
  • Literature
  • Retrieve Sequences
  • Sequence Analysis Tools
  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
  • Maps & Displays
  • Comparison Resources
  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

ADDITIONAL INFORMATION for NDC1

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for NDC1]

1) Hoyt, A.  (1989) Personal Communication, Mortimer Map Edition 10
2) Chial HJ, et al.  (1999) Altered dosage of the Saccharomyces cerevisiae spindle pole body duplication gene, NDC1, leads to aneuploidy and polyploidy. Proc Natl Acad Sci U S A 96(18):10200-5
3) Thomas JH and Botstein D  (1986) A gene required for the separation of chromosomes on the spindle apparatus in yeast. Cell 44(1):65-76
4) Lau CK, et al.  (2004) A novel allele of Saccharomyces cerevisiae NDC1 reveals a potential role for the spindle pole body component Ndc1p in nuclear pore assembly. Eukaryot Cell 3(2):447-58