Standard Name	GAB1 1
Systematic Name	YLR459W
Alias	CDC91 1 , 2
Feature Type	ORF, Verified
Description	GPI transamidase subunit, involved in attachment of glycosylphosphatidylinositol (GPI) anchors to proteins; may have a role in recognition of the attachment signal or of the lipid portion of GPI (2)
Name Description	GPI and Actin Bar 1

Chromosomal Location	ChrXII:1057334 to 1058518 | ORF Map | GBrowse

	View Computational GO annotations for GAB1
Molecular Function
Manually curated	contributes_to GPI-anchor transamidase activity (IC, ISS)
Biological Process
Manually curated	attachment of GPI anchor to protein (IMP)
Cellular Component
Manually curated	GPI-anchor transamidase complex (IMP, IPI)
High-throughput	integral to membrane (ISM)

Classical genetics
conditional	cellular morphology: abnormal heat sensitivity: increased
null	inviable
repressible	actin cytoskeleton morphology: abnormal
Large-scale survey
conditional	colony sectoring: increased
null	inviable
repressible	cytokinesis: abnormal
Resources	PROPHECY | PhenoM | SCMD | ScreenTroll | Yeast Fitness Database

	80 total interaction(s) for 78 unique genes/features.
Physical Interactions	Affinity Capture-RNA: 2 Affinity Capture-Western: 1
Genetic Interactions	Dosage Rescue: 3 Negative Genetic: 64 Positive Genetic: 4 Synthetic Growth Defect: 3 Synthetic Lethality: 3
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | AspGD Homologs | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrXII:1057334 to 1058518 | ORF Map | GBrowse
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..1185 1057334..1058518 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FostersB S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain M22 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000004451