ECM7/YLR443W Summary Help

Standard Name ECM7 1
Systematic Name YLR443W
Alias ZRG15 2
Feature Type ORF, Verified
Description Putative integral membrane protein with a role in calcium uptake; non-essential protein; mutant has cell wall defects and Ca+ uptake deficiencies; transcription is induced under conditions of zinc deficiency (1, 2, 3, 4)
Name Description ExtraCellular Mutant 1
Chromosomal Location
ChrXII:1022625 to 1023971 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All ECM7 GO evidence and references
  View Computational GO annotations for ECM7
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
High-throughput
Regulators 2 genes
Resources
Classical genetics
null
overexpression
unspecified
Large-scale survey
null
unspecified
Resources
37 total interaction(s) for 34 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 1
  • Affinity Capture-RNA: 3
  • Biochemical Activity: 1
  • Reconstituted Complex: 1

Genetic Interactions
  • Negative Genetic: 23
  • Phenotypic Enhancement: 1
  • Positive Genetic: 3
  • Synthetic Growth Defect: 1
  • Synthetic Lethality: 3

Resources
Expression Summary
histogram
Resources
Length (a.a.) 448
Molecular Weight (Da) 50,327
Isoelectric Point (pI) 4.88
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXII:1022625 to 1023971 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1347 1022625..1023971 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000004435
References cited on this page View Complete Literature Guide for ECM7
1) Lussier M, et al.  (1997) Large scale identification of genes involved in cell surface biosynthesis and architecture in Saccharomyces cerevisiae. Genetics 147(2):435-50
2) Yuan DS  (2000) Zinc-regulated genes in Saccharomyces cerevisiae revealed by transposon tagging. Genetics 156(1):45-58
3) Kim H, et al.  (2003) Topology models for 37 Saccharomyces cerevisiae membrane proteins based on C-terminal reporter fusions and predictions. J Biol Chem 278(12):10208-13
4) Martin DC, et al.  (2011) New Regulators of a High Affinity Ca2+ Influx System Revealed through a Genome-wide Screen in Yeast. J Biol Chem 286(12):10744-54