Standard Name	MRPL4 1
Systematic Name	YLR439W
Feature Type	ORF, Verified
Description	Mitochondrial ribosomal protein of the large subunit, homolog of prokaryotic L29 ribosomal protein; located at the ribosomal tunnel exit (1, 2)
Name Description	Mitochondrial Ribosomal Protein, Large subunit 1
Gene Product Alias	YmL4 1

Chromosomal Location	ChrXII:1014491 to 1015450 | ORF Map | GBrowse

	View Computational GO annotations for MRPL4
Molecular Function
Manually curated	structural constituent of ribosome (IDA)
Biological Process
Manually curated	mitochondrial translation (IC, IMP)
Cellular Component
Manually curated	mitochondrial large ribosomal subunit (IDA)
High-throughput	mitochondrion (IDA)

Classical genetics
null	fermentative growth: decreased rate metal resistance: increased mitochondrial genome maintenance: absent respiratory growth: absent
Large-scale survey
null	glycogen accumulation: decreased glutathione excretion: increased competitive fitness: decreased dessication resistance: decreased haploinsufficient heat sensitivity: increased mitochondrial morphology: abnormal resistance to trichothecene: increased respiratory growth: absent respiratory growth: decreased rate stress resistance: increased toxin resistance: increased utilization of carbon source: decreased vacuolar morphology: abnormal vegetative growth: decreased rate viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	64 total interaction(s) for 44 unique genes/features.
Physical Interactions	Affinity Capture-MS: 55 Affinity Capture-RNA: 1 Affinity Capture-Western: 3 Biochemical Activity: 1 Two-hybrid: 2
Genetic Interactions	Dosage Rescue: 1 Synthetic Lethality: 1
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder | YeastRC Two-Hybrid

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | Organelle DB (UMich) | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrXII:1014491 to 1015450 | ORF Map | GBrowse
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..960 1014491..1015450 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB382 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain M22 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain Y10 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000004431