BLS1/YLR408C Summary Help

Standard Name BLS1 1
Systematic Name YLR408C
Feature Type ORF, Verified
Description Subunit of the BLOC-1 complex involved in endosomal maturation; green fluorescent protein (GFP)-fusion protein localizes to the endosome; YLR408C is not an essential gene (1, 2, 3, 4)
Name Description BLoS1-homologue 1
Chromosomal Location
ChrXII:934253 to 933885 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All BLS1 GO evidence and references
  View Computational GO annotations for BLS1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 5 genes
Resources
Large-scale survey
null
Resources
16 total interaction(s) for 13 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 6
  • Affinity Capture-RNA: 1
  • Two-hybrid: 3

Genetic Interactions
  • Negative Genetic: 5
  • Positive Genetic: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 122
Molecular Weight (Da) 14,549
Isoelectric Point (pI) 8.11
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXII:934253 to 933885 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..369 934253..933885 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Retired NameBLB1
Primary SGDIDS000004400
References cited on this page View Complete Literature Guide for BLS1
1) Hayes MJ, et al.  (2011) Yeast Homologues of Three BLOC-1 Subunits Highlight KxDL Proteins As Conserved Interactors of BLOC-1. Traffic 12(3):260-8
2) Giaever G, et al.  (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91
3) Huh WK, et al.  (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91
4) John Peter AT, et al.  (2013) The BLOC-1 complex promotes endosomal maturation by recruiting the Rab5 GTPase-activating protein Msb3. J Cell Biol 201(1):97-111