CST9/YLR394W Summary Help

Standard Name CST9 1
Systematic Name YLR394W
Alias ZIP3 2
Feature Type ORF, Verified
Description SUMO E3 ligase; required for synaptonemal complex formation; localizes to synapsis initiation sites on meiotic chromosomes; potential Cdc28p substrate (2, 3)
Name Description Chromosome STability 1
Chromosomal Location
ChrXII:907950 to 909398 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All CST9 GO evidence and references
  View Computational GO annotations for CST9
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 6 genes
Resources
Classical genetics
null
overexpression
Large-scale survey
null
overexpression
Resources
40 total interaction(s) for 37 unique genes/features.
Physical Interactions
  • Affinity Capture-RNA: 3
  • Affinity Capture-Western: 5
  • Biochemical Activity: 2
  • Two-hybrid: 6

Genetic Interactions
  • Dosage Growth Defect: 2
  • Dosage Lethality: 1
  • Negative Genetic: 11
  • Phenotypic Enhancement: 1
  • Phenotypic Suppression: 3
  • Positive Genetic: 6

Resources
Expression Summary
histogram
Resources
Length (a.a.) 482
Molecular Weight (Da) 53,863
Isoelectric Point (pI) 10.95
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXII:907950 to 909398 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2004-02-05 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1449 907950..909398 2004-02-05 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000004386
References cited on this page View Complete Literature Guide for CST9
1) Ouspenski II, et al.  (1999) New yeast genes important for chromosome integrity and segregation identified by dosage effects on genome stability. Nucleic Acids Res 27(15):3001-8
2) Agarwal S and Roeder GS  (2000) Zip3 provides a link between recombination enzymes and synaptonemal complex proteins. Cell 102(2):245-55
3) Cheng CH, et al.  (2006) SUMO modifications control assembly of synaptonemal complex and polycomplex in meiosis of Saccharomyces cerevisiae. Genes Dev 20(15):2067-81