VID22/YLR373C Summary Help

Standard Name VID22 1
Systematic Name YLR373C
Feature Type ORF, Verified
Description Glycosylated integral membrane protein localized to plasma membrane; plays a role in fructose-1,6-bisphosphatase (FBPase) degradation; involved in FBPase transport from the cytosol to Vid (vacuole import and degradation) vesicles; VID22 has a paralog, ENV11, that arose from the whole genome duplication (1, 2, 3)
Name Description Vacuolar Import and Degradation 1
Chromosomal Location
ChrXII:871367 to 868662 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All VID22 GO evidence and references
  View Computational GO annotations for VID22
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 7 genes
Resources
Classical genetics
null
unspecified
Large-scale survey
null
overexpression
Resources
334 total interaction(s) for 243 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 10
  • Affinity Capture-RNA: 3
  • Affinity Capture-Western: 2
  • Two-hybrid: 1

Genetic Interactions
  • Dosage Rescue: 1
  • Negative Genetic: 196
  • Phenotypic Suppression: 1
  • Positive Genetic: 56
  • Synthetic Growth Defect: 48
  • Synthetic Lethality: 16

Resources
Expression Summary
histogram
Resources
Length (a.a.) 901
Molecular Weight (Da) 102,498
Isoelectric Point (pI) 4.95
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXII:871367 to 868662 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..2706 871367..868662 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000004365
References cited on this page View Complete Literature Guide for VID22
1) Brown CR, et al.  (2002) Vid22p, a novel plasma membrane protein, is required for the fructose-1,6-bisphosphatase degradation pathway. J Cell Sci 115(Pt 3):655-66
2) Brown CR, et al.  (2001) Cyclophilin A mediates Vid22p function in the import of fructose-1,6-bisphosphatase into Vid vesicles. J Biol Chem 276(51):48017-26
3) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61