RSC2/YLR357W Summary Help

RSC2 BASIC INFORMATION

Standard Name RSC2
Systematic Name YLR357W
Feature Type ORF, Verified
Description Component of the RSC chromatin remodeling complex; required for expression of mid-late sporulation-specific genes; involved in telomere maintenance (1, 2, 3, 4)
Name Description Remodel the Structure of Chromatin
GO Annotations All RSC2 GO evidence and references
    View Computational GO annotations for RSC2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Mutant Phenotype All RSC2 Phenotype details and references
Classical genetics
null
Large-scale survey
null
Interactions RSC2 All interactions details and references
  View additional details at BioGRID
315 total interaction(s) for 191 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 105
  • Affinity Capture-Western: 35
  • Co-purification: 6
  • Two-hybrid: 2
Genetic Interactions
  • Dosage Rescue: 3
  • Negative Genetic: 39
  • Phenotypic Enhancement: 2
  • Phenotypic Suppression: 1
  • Positive Genetic: 79
  • Synthetic Growth Defect: 24
  • Synthetic Lethality: 18
  • Synthetic Rescue: 1
Sequence Information
ChrXII:841330 to 843999 | ORF Map | GBrowse
Gbrowse
Last Update Coordinates: 2004-02-05 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..2670 841330..843999 2004-02-05 1996-07-31
Post-translational Modifications PhosphoGRID | PhosphoPep Database
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000004349

RSC2 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
 GBrowse
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  • Sequence Analysis Tools
  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
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  • Comparison Resources
  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

ADDITIONAL INFORMATION for RSC2

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for RSC2]

1) Lorch Y, et al.  (1998) Activated RSC-nucleosome complex and persistently altered form of the nucleosome. Cell 94(1):29-34
2) Neely KE and Workman JL  (2002) The complexity of chromatin remodeling and its links to cancer. Biochim Biophys Acta 1603(1):19-29
3) Bungard D, et al.  (2004) RSC1 and RSC2 are required for expression of mid-late sporulation-specific genes in Saccharomyces cerevisiae. Eukaryot Cell 3(4):910-8
4) Askree SH, et al.  (2004) A genome-wide screen for Saccharomyces cerevisiae deletion mutants that affect telomere length. Proc Natl Acad Sci U S A 101(23):8658-63