GAS2/YLR343W Summary Help

GAS2 BASIC INFORMATION

Standard Name GAS2
Systematic Name YLR343W
Feature Type ORF, Verified
Description 1,3-beta-glucanosyltransferase, involved with Gas4p in spore wall assembly; has similarity to Gas1p (1, 2, 3 and see Summary Paragraph)
GO Annotations All GAS2 GO evidence and references
    View Computational GO annotations for GAS2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
High-throughput
Mutant Phenotype All GAS2 Phenotype details and references
Classical genetics
null
Large-scale survey
null
Interactions GAS2 All interactions details and references
13 total interaction(s) for 13 unique genes/features.
Physical Interactions
  • Two-hybrid: 12
Genetic Interactions
  • Phenotypic Enhancement: 1
Sequence Information
ChrXII:816094 to 817761 | ORF Map | GBrowse
Gbrowse
Last Update Coordinates: 2004-02-05 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..1668 816094..817761 2004-02-05 1996-07-31
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000004335

GAS2 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
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  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

ADDITIONAL INFORMATION for GAS2

SUMMARY PARAGRAPH for GAS2

GAS1, GAS2, GAS3, GAS4, and GAS5 are members of the glycosidase/transglycosidase GH72 family of fungal enzymes involved in cell wall maintenance. They share significant similarity with Aspergillus fumigatus GEL1 and GEL2, and with Candida albicans PHR1 and PHR2. Similar to the most extensively characterized member, Gas1p, the remaining GAS proteins are thought to be cell wall-bound 1,3-beta-glucanosyltransferases involved in cell wall assembly and maintenance (3, 4). Based on their expression patterns, they appear to play partially overlapping roles throughout the development: GAS1 and GAS5 are expressed during vegetative growth, whereas GAS2 and GAS4 are expressed exclusively during sporulation and required for normal spore wall formation (2).

Last updated: 2007-06-01

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for GAS2]

1) Mouyna I, et al.  (2000) Identification of the catalytic residues of the first family of beta(1-3)glucanosyltransferases identified in fungi. Biochem J 347 Pt 3():741-7
2) Ragni E, et al.  (2007) GAS2 and GAS4, a pair of developmentally regulated genes required for spore wall assembly in Saccharomyces cerevisiae. Eukaryot Cell 6(2):302-16
3) Ragni E, et al.  (2007) The Gas family of proteins of Saccharomyces cerevisiae: characterization and evolutionary analysis. Yeast 24(4):297-308
4) Hamada K, et al.  (1999) Amino acid residues in the omega-minus region participate in cellular localization of yeast glycosylphosphatidylinositol-attached proteins. J Bacteriol 181(13):3886-9