SYM1/YLR251W Summary Help

Standard Name SYM1 1
Systematic Name YLR251W
Feature Type ORF, Verified
Description Protein required for ethanol metabolism; induced by heat shock and localized to the inner mitochondrial membrane; homologous to mammalian peroxisomal membrane protein Mpv17 (1)
Name Description Stress-inducible Yeast Mpv17 1
Chromosomal Location
ChrXII:641464 to 642057 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All SYM1 GO evidence and references
  View Computational GO annotations for SYM1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 4 genes
Resources
Classical genetics
null
reduction of function
Large-scale survey
null
overexpression
Resources
35 total interaction(s) for 27 unique genes/features.
Physical Interactions
  • Affinity Capture-RNA: 2
  • Biochemical Activity: 1
  • Reconstituted Complex: 4

Genetic Interactions
  • Dosage Lethality: 1
  • Dosage Rescue: 2
  • Negative Genetic: 19
  • Positive Genetic: 2
  • Synthetic Growth Defect: 4

Resources
Expression Summary
histogram
Resources
Length (a.a.) 197
Molecular Weight (Da) 22,915
Isoelectric Point (pI) 10.75
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXII:641464 to 642057 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..594 641464..642057 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000004241
References cited on this page View Complete Literature Guide for SYM1
1) Trott A and Morano KA  (2004) SYM1 is the stress-induced Saccharomyces cerevisiae ortholog of the mammalian kidney disease gene Mpv17 and is required for ethanol metabolism and tolerance during heat shock. Eukaryot Cell 3(3):620-31