YEF3/YLR249W Summary Help

YEF3 BASIC INFORMATION

Standard Name YEF3 1
Systematic Name YLR249W
Alias TEF3
Feature Type ORF, Verified
Description Translational elongation factor 3, stimulates the binding of aminoacyl-tRNA (AA-tRNA) to ribosomes by releasing EF-1 alpha from the ribosomal complex; contains two ABC cassettes; binds and hydrolyses ATP (1, 2, 3)
Name Description Yeast Elongation Factor 1
GO Annotations All YEF3 GO evidence and references
    View Computational GO annotations for YEF3
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Mutant Phenotype All YEF3 Phenotype details and references
Classical genetics
conditional
overexpression
Large-scale survey
null
Interactions YEF3 All interactions details and references
96 total interaction(s) for 88 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 73
  • Affinity Capture-RNA: 2
  • Affinity Capture-Western: 5
  • Biochemical Activity: 2
  • Two-hybrid: 1
Genetic Interactions
  • Dosage Growth Defect: 1
  • Dosage Rescue: 2
  • Phenotypic Enhancement: 4
  • Phenotypic Suppression: 5
  • Synthetic Lethality: 1
Sequence Information
ChrXII:636782 to 639916 | ORF Map | GBrowse
Gbrowse
Last Update Coordinates: 2004-02-05 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..3135 636782..639916 2004-02-05 1996-07-31
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000004239

YEF3 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
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  • Literature
  • Retrieve Sequences
  • Sequence Analysis Tools
  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
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  • Comparison Resources
  • Functional Analysis

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Expression Summary histogram

ADDITIONAL INFORMATION for YEF3

NOMENCLATURE CONFLICT NOTE

NameRelevanceDescription
CAM1Nomenclature conflictThe gene name alias "TEF3" has been used to refer to both YEF3/YLR249W, the translation elongation factor 3 (EF-3), and CAM1/YPL048W, a protein homologous to translation elongation factor 1-gamma (EF-1gamma).

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for YEF3]

1) Qin SL, et al.  (1987) Isolation of the yeast gene encoding elongation factor 3 for protein synthesis. J Biol Chem 262(16):7802-7
2) Kamath A and Chakraburtty K  (1989) Role of yeast elongation factor 3 in the elongation cycle. J Biol Chem 264(26):15423-8
3) Miyazaki M, et al.  (1986) Intrinsic ATPase activity of yeast peptide chain elongation factor 3(EF-3) and its direct interaction with various nucleotides. Nucleic Acids Symp Ser(17):171-4