SHH4/YLR164W Summary Help

Standard Name SHH4 1
Systematic Name YLR164W
Feature Type ORF, Verified
Description Mitochondrial inner membrane protein of unknown function; similar to Tim18p; a fraction copurifies with Sdh3p, but Shh4p is neither a stoichiometric subunit of succinate dehydrogenase nor of the TIM22 translocase; expression induced by nitrogen limitation in a GLN3, GAT1-dependent manner; SHH4 has a paralog, SDH4, that arose from the whole genome duplication (1, 2, 3, 4)
Name Description SDH4 Homolog 1
Chromosomal Location
ChrXII:493883 to 494389 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All SHH4 GO evidence and references
  View Computational GO annotations for SHH4
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 5 genes
Resources
Large-scale survey
null
Resources
7 total interaction(s) for 7 unique genes/features.
Physical Interactions
  • Affinity Capture-RNA: 2
  • Affinity Capture-Western: 1

Genetic Interactions
  • Dosage Rescue: 1
  • Negative Genetic: 3

Resources
Expression Summary
histogram
Resources
Length (a.a.) 168
Molecular Weight (Da) 18,632
Isoelectric Point (pI) 10.19
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXII:493883 to 494389 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..507 493883..494389 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000004154
References cited on this page View Complete Literature Guide for SHH4
1) Gebert N, et al.  (2011) Dual Function of Sdh3 in the Respiratory Chain and TIM22 Protein Translocase of the Mitochondrial Inner Membrane. Mol Cell 44(5):811-8
2) Kerscher O, et al.  (2000) Tim18p is a new component of the Tim54p-Tim22p translocon in the mitochondrial inner membrane. Mol Biol Cell 11(1):103-16
3) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61
4) Scherens B, et al.  (2006) Identification of direct and indirect targets of the Gln3 and Gat1 activators by transcriptional profiling in response to nitrogen availability in the short and long term. FEMS Yeast Res 6(5):777-91