ACF2/YLR144C Summary Help

ACF2 BASIC INFORMATION

Standard Name ACF2
Systematic Name YLR144C
Alias ENG2 , PCA1
Feature Type ORF, Verified
Description Intracellular beta-1,3-endoglucanase, expression is induced during sporulation; may have a role in cortical actin cytoskeleton assembly (1, 2, 3)
Name Description Assembly Complementing Factor 1
GO Annotations All ACF2 GO evidence and references
    View Computational GO annotations for ACF2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Mutant Phenotype All ACF2 Phenotype details and references
Large-scale survey
null
Interactions ACF2 All interactions details and references
38 total interaction(s) for 27 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 9
  • Affinity Capture-RNA: 2
  • Affinity Capture-Western: 1
  • PCA: 10
  • Protein-peptide: 3
  • Two-hybrid: 12

Genetic Interactions
  • Synthetic Growth Defect: 1

Sequence Information
ChrXII:432017 to 429678 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Last Update Coordinates: 1996-07-31 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..2340 432017..429678 1996-07-31 1996-07-31
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000004134

ACF2 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
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  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

NOMENCLATURE CONFLICT NOTE

NameRelevanceDescription
PCA1Nomenclature conflictBoth PCA1/YBR295W, which encodes a cation-transporting ATPase, and ACF2/YLR144C, which encodes a glucan 1,3-beta-glucosidase, have been referred to as PCA1.

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for ACF2]

1) Lechler T and Li R  (1997) In vitro reconstitution of cortical actin assembly sites in budding yeast. J Cell Biol 138(1):95-103
2) Baladron V, et al.  (2002) Eng1p, an endo-1,3-beta-glucanase localized at the daughter side of the septum, is involved in cell separation in Saccharomyces cerevisiae. Eukaryot Cell 1(5):774-86
3) Martin-Cuadrado AB, et al.  (2008) Characterization of the endo-beta-1,3-glucanase activity of S. cerevisiae Eng2 and other members of the GH81 family. Fungal Genet Biol 45(4):542-53