RRN5/YLR141W Summary

RRN5 BASIC INFORMATION

Standard Name	RRN5 1
Systematic Name	YLR141W
Feature Type	ORF, Verified
Description	Protein involved in transcription of rDNA by RNA polymerase I; transcription factor, member of UAF (upstream activation factor) family along with Rrn9p and Rrn10p (2)
Name Description	Regulation of RNA polymerase I 1

GO Annotations	All RRN5 GO evidence and references
	View Computational GO annotations for RRN5
Molecular Function
Manually curated	rDNA binding (TAS) RNA polymerase I transcription factor activity (TAS)
Biological Process
Manually curated	transcription from RNA polymerase I promoter (TAS) transcription of nuclear rRNA large RNA polymerase I transcript (IGI)
Cellular Component
Manually curated	RNA polymerase I upstream activating factor complex (TAS)

Mutant Phenotype	All RRN5 Phenotype details and references
Classical genetics
conditional	rRNA species transcribed by RNA polymerase I accumulation: decreased heat sensitivity: increased
Large-scale survey
conditional	heat sensitivity: increased
null	inviable

Interactions	RRN5 All interactions details and references
	16 total interaction(s) for 12 unique genes/features.
Physical Interactions	Affinity Capture-MS: 7 Affinity Capture-RNA: 1 Affinity Capture-Western: 2 Co-purification: 2 Two-hybrid: 1
Genetic Interactions	Dosage Rescue: 1 Synthetic Lethality: 1 Synthetic Rescue: 1

Sequence Information

ChrXII:423684 to 424775 | |

Last Update

Coordinates: 1996-07-31 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..1092	423684..424775	1996-07-31	1996-07-31

External Links	All Associated Seq \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000004131

RRN5 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for RRN5

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for RRN5]

1)	Nogi Y, et al. (1991) An approach for isolation of mutants defective in 35S ribosomal RNA synthesis in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 88(16):7026-30
2)	Keys DA, et al. (1996) Multiprotein transcription factor UAF interacts with the upstream element of the yeast RNA polymerase I promoter and forms a stable preinitiation complex. Genes Dev 10(7):887-903

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