Standard Name	RRN5 1
Systematic Name	YLR141W
Feature Type	ORF, Verified
Description	Protein involved in transcription of rDNA by RNA polymerase I; transcription factor, member of UAF (upstream activation factor) family along with Rrn9p and Rrn10p (2)
Name Description	Regulation of RNA polymerase I 1

Chromosomal Location	ChrXII:423683 to 424774 | ORF Map | GBrowse

	View Computational GO annotations for RRN5
Molecular Function
Manually curated	contributes_to RNA polymerase I upstream control element sequence-specific DNA binding transcription factor activity (IDA)
Biological Process
Manually curated	chromatin organization (IMP) transcription of nuclear large rRNA transcript from RNA polymerase I promoter (IDA, IMP)
Cellular Component
Manually curated	nucleolus (IDA) RNA polymerase I upstream activating factor complex (IDA)

Classical genetics
conditional	rRNA species transcribed by RNA polymerase I accumulation: decreased heat sensitivity: increased
Large-scale survey
conditional	heat sensitivity: increased
null	inviable
reduction of function	competitive fitness: increased
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	26 total interaction(s) for 18 unique genes/features.
Physical Interactions	Affinity Capture-MS: 15 Affinity Capture-RNA: 1 Affinity Capture-Western: 2 Co-purification: 2 Two-hybrid: 1
Genetic Interactions	Dosage Rescue: 1 Synthetic Lethality: 3 Synthetic Rescue: 1
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP
Homologs	Ashbya (AGD) | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrXII:423683 to 424774 | ORF Map | GBrowse
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..1092 423683..424774 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain Y10 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000004131