Standard Name	SLS1 (see Nomenclature conflict Note)
Systematic Name	YLR139C
Feature Type	ORF, Verified
Description	Mitochondrial membrane protein that coordinates expression of mitochondrially-encoded genes; may facilitate delivery of mRNA to membrane-bound translation machinery (1, 2, 3)
Name Description	Sigma Like Sequence

Chromosomal Location	ChrXII:423473 to 421542 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.

	View Computational GO annotations for SLS1
Molecular Function
Manually curated	molecular_function unknown (ND)
Biological Process
Manually curated	aerobic respiration (IMP) mitochondrial translation (IMP)
Cellular Component
Manually curated	integral to membrane (IDA) mitochondrial inner membrane (IDA) mitochondrial nucleoid (IDA)
High-throughput	mitochondrion (IDA)

Classical genetics
null	respiratory growth: absent viable
Large-scale survey
null	glycogen accumulation: decreased glutathione excretion: increased competitive fitness: decreased endocytosis: decreased haploinsufficient heat sensitivity: increased metal resistance: increased mitochondrial morphology: abnormal resistance to 4-chlorophenol: decreased resistance to trichothecene: increased resistance to doxorubicin: decreased resistance to acrolein: decreased resistance to glycolaldehyde: decreased resistance to 2,4-dichlorophenol: decreased resistance to pentachlorophenol: decreased resistance to nickel sulfate: increased respiratory growth: absent respiratory growth: decreased rate stress resistance: increased toxin resistance: decreased utilization of carbon source: decreased vegetative growth: decreased rate viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	62 total interaction(s) for 56 unique genes/features.
Physical Interactions	Affinity Capture-MS: 15 Affinity Capture-RNA: 1
Genetic Interactions	Dosage Lethality: 1 Dosage Rescue: 2 Negative Genetic: 26 Positive Genetic: 16 Synthetic Lethality: 1
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | Organelle DB (UMich) | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP
Homologs	Ashbya (AGD) | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrXII:423473 to 421542 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..1932 423473..421542 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CEN.PK113-7D S.c. Strain EC1118 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000004129