NHA1/YLR138W Summary Help

Standard Name NHA1 1
Systematic Name YLR138W
Feature Type ORF, Verified
Description Na+/H+ antiporter; involved in sodium and potassium efflux through the plasma membrane; required for alkali cation tolerance at acidic pH (1, 2)
Name Description Na+/H+ Antiporter 1
Chromosomal Location
ChrXII:418437 to 421394 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All NHA1 GO evidence and references
  View Computational GO annotations for NHA1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 3 genes
Resources
Classical genetics
null
reduction of function
Large-scale survey
null
overexpression
unspecified
Resources
60 total interaction(s) for 44 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 4
  • Affinity Capture-RNA: 2
  • Affinity Capture-Western: 3
  • Biochemical Activity: 1
  • Co-fractionation: 1
  • PCA: 5
  • Reconstituted Complex: 1

Genetic Interactions
  • Dosage Rescue: 7
  • Negative Genetic: 10
  • Phenotypic Enhancement: 6
  • Positive Genetic: 8
  • Synthetic Growth Defect: 10
  • Synthetic Lethality: 1
  • Synthetic Rescue: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 985
Molecular Weight (Da) 109,368
Isoelectric Point (pI) 5.26
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXII:418437 to 421394 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..2958 418437..421394 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | TCDB | UniProtKB
Primary SGDIDS000004128
References cited on this page View Complete Literature Guide for NHA1
1) Prior C, et al.  (1996) Characterization of the NHA1 gene encoding a Na+/H+-antiporter of the yeast Saccharomyces cerevisiae. FEBS Lett 387(1):89-93
2) Banuelos MA, et al.  (1998) The Nha1 antiporter of Saccharomyces cerevisiae mediates sodium and potassium efflux. Microbiology 144 ( Pt 10)():2749-58