YPS1/YLR120C Summary

YPS1 BASIC INFORMATION

Standard Name	YPS1
Systematic Name	YLR120C
Alias	YAP3
Feature Type	ORF, Verified
Description	Aspartic protease, attached to the plasma membrane via a glycosylphosphatidylinositol (GPI) anchor (1)
Name Description	YaPSin

GO Annotations	All YPS1 GO evidence and references
	View Computational GO annotations for YPS1
Molecular Function
Manually curated	aspartic-type endopeptidase activity (IDA)
Biological Process
Manually curated	protein processing (IDA)
Cellular Component
Manually curated	fungal-type cell wall (IDA)

Mutant Phenotype	All YPS1 Phenotype details and references
Classical genetics
null	resistance to St. John's Wort extract: decreased
Large-scale survey
null	competitive fitness: decreased resistance to St. John's Wort extract: decreased resistance to doxorubicin: decreased viable

Interactions	YPS1 All interactions details and references
	22 total interaction(s) for 11 unique genes/features.
Physical Interactions	Affinity Capture-RNA: 1 Two-hybrid: 1
Genetic Interactions	Dosage Rescue: 3 Phenotypic Enhancement: 8 Phenotypic Suppression: 4 Synthetic Growth Defect: 1 Synthetic Haploinsufficiency: 1 Synthetic Lethality: 3

Sequence Information

ChrXII:388221 to 386512 | |

Note: this feature is encoded on the Crick strand.

Last Update

Coordinates: 1996-07-31 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..1710	388221..386512	1996-07-31	1996-07-31

External Links	All Associated Seq \| E.C. \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000004110

YPS1 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for YPS1

NOMENCLATURE CONFLICT NOTE

Name	Relevance	Description
YAP3	Nomenclature conflict	YAP3 has been used in the literature to refer to both YPS1/YLR120C which encodes an aspartic protease, and YAP3/YHL009C which encodes a transcription factor.

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for YPS1]

1)	Cawley NX, et al. (1995) Secretion of yeast aspartic protease 3 is regulated by its carboxy-terminal tail: characterization of secreted YAP3p. Biochemistry 34(22):7430-7

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