CCW12/YLR110C Summary Help

Standard Name CCW12 1
Systematic Name YLR110C
Feature Type ORF, Verified
Description Cell wall mannoprotein; plays a role in maintenance of newly synthesized areas of cell wall; localizes to periphery of small buds, septum region of larger buds, and shmoo tip; CCW12 has a paralog, YDR134C, that arose from the whole genome duplication (1, 2, 3, 4)
Name Description Covalently linked Cell Wall protein 1
Chromosomal Location
ChrXII:370098 to 369697 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All CCW12 GO evidence and references
  View Computational GO annotations for CCW12
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 18 genes
Resources
Classical genetics
null
overexpression
Large-scale survey
null
Resources
299 total interaction(s) for 199 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 3
  • Affinity Capture-RNA: 8
  • Co-purification: 1
  • PCA: 4

Genetic Interactions
  • Dosage Rescue: 5
  • Negative Genetic: 126
  • Phenotypic Enhancement: 28
  • Phenotypic Suppression: 42
  • Positive Genetic: 28
  • Synthetic Growth Defect: 29
  • Synthetic Lethality: 25

Resources
Expression Summary
histogram
Resources
Length (a.a.) 133
Molecular Weight (Da) 13,057
Isoelectric Point (pI) 4.38
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXII:370098 to 369697 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..402 370098..369697 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000004100
References cited on this page View Complete Literature Guide for CCW12
1) Mrsa V, et al.  (1999) Deletion of new covalently linked cell wall glycoproteins alters the electrophoretic mobility of phosphorylated wall components of Saccharomyces cerevisiae. J Bacteriol 181(10):3076-86
2) Seidel J and Tanner W  (1997) Characterization of two new genes down-regulated by alpha-factor. Yeast 13(9):809-17
3) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61
4) Ragni E, et al.  (2011) The genetic interaction network of CCW12, a Saccharomyces cerevisiae gene required for cell wall integrity during budding and formation of mating projections. BMC Genomics 12():107