STU2/YLR045C Summary Help

STU2 BASIC INFORMATION

Standard Name STU2
Systematic Name YLR045C
Feature Type ORF, Verified
Description Microtubule-associated protein (MAP) of the XMAP215/Dis1 family; regulates microtubule dynamics during spindle orientation and metaphase chromosome alignment; interacts with spindle pole body component Spc72p (1, 2, 3, 4)
Name Description Suppressor of tub2
GO Annotations All STU2 GO evidence and references
    View Computational GO annotations for STU2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Mutant Phenotype All STU2 Phenotype details and references
Classical genetics
null
Large-scale survey
null
Interactions STU2 All interactions details and references
60 total interaction(s) for 31 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 3
  • Affinity Capture-Western: 12
  • Biochemical Activity: 3
  • Co-purification: 1
  • PCA: 2
  • Reconstituted Complex: 4
  • Two-hybrid: 26
Genetic Interactions
  • Phenotypic Enhancement: 3
  • Phenotypic Suppression: 1
  • Synthetic Growth Defect: 2
  • Synthetic Lethality: 1
  • Synthetic Rescue: 2
Sequence Information
ChrXII:237704 to 235038 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Last Update Coordinates: 1996-07-31 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..2667 237704..235038 1996-07-31 1996-07-31
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000004035

STU2 RESOURCES

Click on map for expanded view
SGD ORF mapGBrowse
SGD ORF map
 GBrowse
  • Literature
  • Retrieve Sequences
  • Sequence Analysis Tools
  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
  • Maps & Displays
  • Comparison Resources
  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

ADDITIONAL INFORMATION for STU2

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for STU2]

1) Chen XP, et al.  (1998) The yeast spindle pole body component Spc72p interacts with Stu2p and is required for proper microtubule assembly. J Cell Biol 141(5):1169-79
2) Wang PJ and Huffaker TC  (1997) Stu2p: A microtubule-binding protein that is an essential component of the yeast spindle pole body. J Cell Biol 139(5):1271-80
3) Severin F, et al.  (2001) Stu2 promotes mitotic spindle elongation in anaphase. J Cell Biol 153(2):435-42
4) Kosco KA, et al.  (2001) Control of microtubule dynamics by Stu2p is essential for spindle orientation and metaphase chromosome alignment in yeast. Mol Biol Cell 12(9):2870-80