RLP24/YLR009W Summary Help

Standard Name RLP24 1
Systematic Name YLR009W
Feature Type ORF, Verified
Description Essential protein required for ribosomal large subunit biogenesis; associated with pre-60S ribosomal subunits; stimulates the ATPase activity of Afg2p, which is required for release of Rlp24p from the pre-60S particle; has similarity to Rpl24Ap and Rpl24Bp (1, 2, 3)
Name Description Ribosomal-Like Protein 1, 2
Chromosomal Location
ChrXII:166537 to 167136 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All RLP24 GO evidence and references
  View Computational GO annotations for RLP24
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 4 genes
Resources
Large-scale survey
null
overexpression
reduction of function
Resources
101 total interaction(s) for 62 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 65
  • Affinity Capture-RNA: 3
  • Affinity Capture-Western: 26
  • Biochemical Activity: 1
  • Two-hybrid: 2

Genetic Interactions
  • Dosage Rescue: 2
  • Synthetic Growth Defect: 2

Resources
Expression Summary
histogram
Resources
Length (a.a.) 199
Molecular Weight (Da) 23,975
Isoelectric Point (pI) 10.35
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXII:166537 to 167136 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..600 166537..167136 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000003999
References cited on this page View Complete Literature Guide for RLP24
1) Harnpicharnchai P, et al.  (2001) Composition and functional characterization of yeast 66S ribosome assembly intermediates. Mol Cell 8(3):505-15
2) Saveanu C, et al.  (2001) Nog2p, a putative GTPase associated with pre-60S subunits and required for late 60S maturation steps. EMBO J 20(22):6475-84
3) Kappel L, et al.  (2012) Rlp24 activates the AAA-ATPase Drg1 to initiate cytoplasmic pre-60S maturation. J Cell Biol 199(5):771-82